knee injection
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Last Updated On: June 7, 2024

Orthovisc Knee Injections: Indications, Techniques, and Efficacy

Published on: May 3, 2024

According to the Centers for Disease Control and Prevention (CDC), nearly 27 million adults in the United States are affected by knee osteoarthritis. This prevalence pushes individuals suffering from this degenerative disease to look for solutions that would allow them to regain their mobility while relieving the pain in their joints. 

Orthovisc is a highly safe and effective treatment for joint pain, especially in the knee. Its hyaluronic acid content acts as a lubricant and protects the joints, offering significant pain relief and improved mobility. With this innovative approach to osteoarthritis, Orthovisc injections have become popular for patients seeking long-lasting relief from knee pain.

This article will explore the benefits of Orthovisc as a hyaluronic acid treatment, focusing on its indications, techniques, and efficacy. 

Key Takeaways

  • Orthovisc is a knee injection for osteoarthritis pain. It uses hyaluronic acid to help knees move better.
  • Doctors give these shots to people who didn’t get better with other treatments. It’s suitable for ages 40 to 65 without severe joint damage.
  • The way doctors inject Orthovisc is essential. Clean skin and the right spot help make it work well.
  • Studies show that Orthovisc can reduce knee pain. Many feel better for up to six months after getting injections.
  • Choosing the right patients is key to good results. People need clear expectations and should follow care advice after shots.

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Introduction to Orthovisc Knee Injections

Orthovisc knee injections effectively treat osteoarthritis-related knee pain, utilizing a specialized form of hyaluronic acid. This treatment significantly reduces pain and improves mobility in the knee joint. Studies have shown that Orthovisc injections can provide long-lasting relief, although the number of injections required may vary for each patient. 

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While Orthovisc is primarily used for knee osteoarthritis, its efficacy in other joints has not been established in U.S.-based studies. Patients may ask questions like, “Is Orthovisc steroid?” For that, they should discuss potential side effects with their doctor before starting treatment and follow their doctor’s advice regarding post-injection exercises.

Role of Orthovisc in Knee Osteoarthritis Treatment

Orthovisc is a high molecular weight injectable hyaluronic acid viscosupplement used to treat knee pain from osteoarthritis. It improves lubrication, reduces friction, and enhances joint mobility by replacing or supplementing the diseased joint’s synovial fluid. Studies show that Orthovisc injections relieve symptomatic pain and improve joint function, with the number of injections and dosage tailored to individual needs.

Indications for Orthovisc Knee Injections

Doctors choose Orthovisc for patients with knee osteoarthritis when other treatments don’t work. The treatment is for those needing more relief after trying basics like diet changes and exercise. It ensures that those who get the shots have the best chance for relief from knee osteoarthritis pain.

  1. Diagnosis of knee osteoarthritis: Patients should have a precise diagnosis of knee osteoarthritis, which causes joint pain and stiffness.
  2. Lack of response to other treatments: Patients should have tried other treatments like physical therapy or pain relievers without sufficient improvement.
  3. Suitable age range: Typically, patients aged 40 to 65 are ideal candidates for Orthovisc injections.
  4. Joint structure integrity: Orthovisc is most effective in knees, with some remaining structural integrity.
  5. No allergy history: Patients with allergies to bird proteins, feathers, or egg products should avoid Orthovisc to prevent reactions.
  6. Understanding and consent: Patients must understand and agree to the Orthovisc treatment plan.
  7. Physical health status: Generally good health supports better outcomes with Orthovisc injections.
  8. Realistic expectations: Patients should have realistic expectations about Orthovisc, understanding it relieves pain but isn’t a cure.
  9. Willingness to follow post-injection advice: Patients should be willing to follow post-injection guidelines to maximize benefits.
  10. Review side effects: Patients should discuss potential side effects like soreness or swelling at the injection site before treatment.

Severity of Knee Osteoarthritis for Orthovisc Treatment

Orthovisc treatment targets patients with mild to moderate knee osteoarthritis, offering significant pain relief and improved joint mobility. It’s a viable option for those whose knee pain persists despite basic treatments like exercise or pain medication. Orthovisc injections aim to alleviate pain and restore mobility, allowing patients to resume their daily activities without discomfort. 

Each patient requires a personalized treatment plan to determine the optimal number of injections for the best results. With Orthovisc, patients can find relief from knee pain and regain the ability to enjoy their favorite activities.

Injection Techniques for Orthovisc

Administering Orthovisc knee injections requires precision and attention to detail. This procedure aims to relieve pain from osteoarthritis and improve joint mobility. Here is a step-by-step guide for medical professionals on how to properly administer these injections:

  • Confirm knee osteoarthritis diagnosis and patient suitability for Orthovisc treatment based on the severity of the condition.
  • Gather necessary supplies: Orthovisc dose, syringe, needle, gloves, antiseptic solution, and sterile gauze.
  • Position the patient comfortably, exposing the knee for injection site access.
  • Clean the injection area with an antiseptic solution, ensuring it dries completely.
  • Aspire excess fluid from the knee joint to enhance treatment efficacy.
  • Attach the needle to a syringe filled with Orthovisc, remove air bubbles, and prepare for injection.
  • Locate the injection site, usually at the side of the kneecap where it is softest.
  • Insert the needle into the knee joint at a recommended angle for intra-articular injections.
  • Slowly inject Orthovisc into the knee joint cavity to minimize patient discomfort.
  • Withdraw the needle, apply pressure to stop bleeding, and avoid rubbing the injection site.
  • Advise patient to avoid stressing treated knee for 48 hours post-injection.
  • Schedule follow-up appointments according to Orthovisc dosing guidelines for optimal results.
  • Monitor patient closely for Orthovisc side effects, addressing them promptly if they occur.
  • Provide aftercare advice, including tailored exercise recommendations for optimal recovery.

Best Practices for Injection Site Selection and Preparation

After learning how to give Orthovisc knee injections, focusing on where and how to inject them properly is crucial. Selecting and preparing the injection site are key steps for a successful treatment. Hereā€™s what you need to do:

  • Thoroughly clean the skin with an antiseptic solution to prevent infection at the injection site.
  • Choose the correct injection site within the knee joint, avoiding swollen or inflamed areas.
  • Use bony landmarks around the knee to guide injection placement.
  • Ensure the patient is comfortable, lying down or sitting with their knee slightly bent.
  • Wear gloves to maintain sterility and protect against infection.
  • Use a fresh needle and syringe for each injection to prevent contamination.
  • Mark the injection site with a non-permanent marker before disinfecting, if necessary.
  • Apply gentle pressure after injection to stop bleeding, avoiding deep massage.
  • Communicate with the patient throughout the procedure to keep them calm and informed.
  • Adjust the lighting for optimal visibility during injections, ensuring precision and accuracy.

Efficacy of Orthovisc Knee Injections

Orthovisc knee injections provide effective relief from severe knee pain for up to six months. Clinical studies demonstrate Orthovisc’s efficacy in treating knee osteoarthritis, significantly improving pain and mobility. 

Patients experience enhanced knee function and reduced pain, making Orthovisc a trusted option for managing osteoarthritis symptoms. With its proven ability to alleviate discomfort and improve knee function, Orthovisc injections offer patients a reliable solution for long-term relief from knee osteoarthritis.

Expected Outcomes and Duration of Pain Relief

Transitioning from Orthovisc’s effectiveness, let’s discuss patient outcomes regarding pain relief and its duration. Patients often experience significant knee pain reduction, enhancing mobility and daily activities. 

Typically, relief becomes noticeable a few weeks after the first injection. While the duration varies, many enjoy pain relief for up to six months or longer before requiring additional injections. Individual responses and osteoarthritis severity influence these outcomes. Regular follow-ups help tailor ongoing care for optimal treatment benefits.


Orthovisc knee injections offer a valuable treatment option for patients with knee osteoarthritis who have not responded to conservative therapies. By carefully considering patient selection criteria, employing proper injection techniques, and understanding the expected outcomes, medical professionals can effectively incorporate Orthovisc into their treatment regimens, ultimately improving the quality of life for individuals suffering from knee joint degeneration.


1. What is Orthovisc, and how does it work for knee pain?

Orthovisc is not a steroid; it’s a thick fluid that doctors inject into your knee to help with pain. It acts like the natural fluid in your knees, making them move smoothly.

2. How often do you need Orthovisc injections?

The usual plan includes getting three or four shots over several weeks. Each shot gives you some special fluid to help your knee hurt less.

3. Will I see good results from Orthovisc injections?

Many people find their knees feel much better after getting these shots because they provide extra cushioning and lubrication inside the joint. Your doctor can tell you more about what to expect!

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Using Orthovisc in Viscosupplementation. Verywell Health.

Orthovisc Injection Information. Accessed April 29, 2024.