Euflexxa for Shoulder
Euflexxa
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Last Updated On October 17, 2024

Euflexxa For Shoulder – Is It a Good Treatment?

Oct 15, 2024

A study published in BMC Musculoskeletal Disorders found that shoulder osteoarthritis (OA) affects as many as one-third of patients over the age of 60, causing significant pain and reduced mobility. This underscores the need for effective treatment options to manage the condition better and improve patients’ quality of life.

Euflexxa, a well-known viscosupplement primarily used for knee OA, is now being explored as a treatment for shoulder OA. Euflexxa aims to relieve pain and enhance joint function by supplementing the shoulder joint’s natural lubrication. Understanding its efficacy and safety for shoulder OA is crucial for expanding treatment options.

In this article, we will explore the use of Euflexxa for shoulder osteoarthritis, discussing its potential benefits, application methods, and patient outcomes to assess whether it is a viable treatment option.

Key Takeaways

  • Euflexxa is a hyaluronic acid-based injection traditionally used to treat knee osteoarthritis but is now being explored for shoulder osteoarthritis (OA).
  • It acts as a lubricant, mimicking natural joint fluid to reduce pain and improve mobility in the shoulder joint.
  • Studies show that Euflexxa effectively reduces pain and stiffness for patients with early to moderate shoulder OA when used as part of a three-injection series.
  • Rehabilitation after treatment, including light exercises, physical therapy, and avoiding stress on the shoulder, is vital to achieving the best outcomes.
  • While generally well-tolerated, Euflexxa can have mild side effects, such as pain or swelling at the injection site. More serious side effects, like allergic reactions, are rare.
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Understanding Euflexxa Injections

Euflexxa is a 1% sodium hyaluronate solution originally developed for treating knee osteoarthritis but is now being explored as a promising option for shoulder osteoarthritis. This injectable supplements the joint’s natural synovial fluid. For shoulder osteoarthritis, Euflexxa is most effective in joints with minimal inflammation, helping to restore mobility and relieve discomfort.

The hyaluronic acid in Euflexxa reduces friction in the shoulder joint, leading to an improved range of motion and decreased pain over time. Studies suggest that patients with early to moderate shoulder OA may benefit most from this treatment, as it targets the joint’s natural lubrication rather than inflammation.

Compared to other treatment options, Euflexxa offers distinct advantages. Unlike corticosteroid injections, which provide short-term relief by reducing inflammation, Euflexxa improves joint function through longer-lasting lubrication.

While physical therapy strengthens muscles and improves mobility, Euflexxa directly addresses joint mechanics, making it a suitable alternative for those not responding to conservative methods.

Effectiveness of Euflexxa for Shoulder Osteoarthritis

Euflexxa has shown promise in treating shoulder osteoarthritis (OA). In a small-scale study, 27 subjects with glenohumeral osteoarthritis received weekly injections of high molecular weight hyaluronate for three weeks. 

The results were assessed over a 26-week period using various measures, including the Visual Analog Scale (VAS) for pain, the Western Ontario and McMaster Universities Arthritis Index (WOMAC), and the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT)-Osteoarthritis Research Society International (OARSI) criteria.

The findings indicated significant improvements in pain, stiffness, and physical functioning. Specifically, 77.8% of subjects were rated as having a high response according to the OMERACT-OARSI criteria. Additionally, no serious adverse events were reported, suggesting that Euflexxa is both effective and well-tolerated for managing shoulder OA.

Patient Testimonials and Experiences

People with shoulder pain from osteoarthritis have tried Euflexxa. Some say it helps a lot. Here’s what they shared:

  • Grand: “Osteoarthritis is part of my life in hips, shoulders, ankles, and, most of all, those knees. My knees are bone-on-bone, and cortisone (not good for long term) is not long-lasting…On a scale of 0-10, my pain was 9.9, and now I am at minimal discomfort around a 3. Hoping it lasts for the full six months. It is wonderful to go up and down stairs forward rather than turning sideways.”

Potential Side Effects and Risks

Euflexxa is usually well-tolerated for treating shoulder osteoarthritis, but like any treatment, there are some potential side effects to keep in mind. The most common issues include pain, swelling, or redness around the injection site, but these symptoms typically go away after a few days. 

People might sometimes experience joint stiffness, headaches, or even nausea after treatment. While these side effects are less common and usually don’t last long, mentioning them to your doctor is always a good idea if they stick around.

Though rare, more serious side effects can happen. These might include severe allergic reactions, like trouble breathing, facial or throat swelling, or a rash. There’s also a small chance of infection, especially if the injection isn’t given under sterile conditions. In some cases, patients may experience severe joint pain or significant swelling in the shoulder after the injection, which would need immediate medical attention.

What to Expect from Euflexxa Treatment for Shoulder Osteoarthritis

Euflexxa offers a promising option for those dealing with shoulder osteoarthritis (OA) by relieving pain and improving joint function through a series of injections. Here’s what the process typically looks like:

  • Consultation: Your doctor will assess whether Euflexxa is suitable for your shoulder OA based on your medical history and symptoms.
  • First Injection: If you’re eligible, the first Euflexxa injection will be administered. This shot is designed to improve lubrication in your shoulder joint, helping to reduce pain and enhance movement.
  • Follow-up Injections: Typically, three injections are given, spaced one week apart. Each injection builds up lubrication in the joint, offering cumulative benefits.
  • Notice Improvements: Most patients notice improvements in pain relief and mobility after completing the series of injections, with results peaking after the final shot.
  • Follow-up Appointment: Around a month after your last injection, you’ll have a follow-up appointment with your doctor to assess the effectiveness of the treatment and plan any further care.
  • Long-term Care: The effects of Euflexxa typically last for several months. In addition to the injections, continuing with physiotherapy or gentle exercises can help maintain joint strength and flexibility.
  • Additional Treatments: Depending on your condition and how well your shoulder responds to the treatment, your doctor may recommend additional rounds of Euflexxa to extend the benefits.

Euflexxa could offer significant relief from shoulder OA by acting as an artificial synovial fluid. The Euflexxa manufacturer designed it to improve pain levels and range of motion without the severe side effects typical of other treatments.

Rehabilitation and Post-injection Care 

After receiving Euflexxa injections, proper care is key to ensuring a smooth recovery and optimal results. Follow these steps to help your shoulder heal and regain strength:

  • Start with light exercises soon after the injections to boost mobility and strength in the shoulder joint.
  • Ice packs can be applied to the treated area for 15-20 minutes at a time to reduce swelling and ease discomfort.
  • For the first few weeks, avoid heavy lifting or putting excessive stress on the shoulder. Focus on gentle activities to promote healing.
  • Regular follow-up appointments with your doctor will help monitor your progress and adjust your care if needed.
  • Physical therapy may be recommended as part of your recovery plan to improve movement and reduce pain over time.
  • Take any pain relief medications as your doctor advises, but avoid overuse.
  • Keep a daily journal to track changes in your pain levels and how the shoulder feels throughout the recovery period.
  • If your doctor advises, use a support sling to protect the shoulder and prevent overexertion.
  • Maintaining a healthy diet and staying hydrated will support your body’s natural healing processes.

Making Informed Decisions about Euflexxa for Shoulder Osteoarthritis

When considering Euflexxa for treating shoulder osteoarthritis (OA), it’s important to weigh both the potential benefits and the associated risks. While Euflexxa has shown effectiveness in relieving pain and improving joint function in patients with knee OA, growing evidence suggests it can offer similar benefits for shoulder OA.

Its success largely depends on factors such as the severity of your condition, the presence of inflammation, and how your body responds to the treatment. To make an informed decision, consult a healthcare professional who can assess whether Euflexxa is suitable for you.

Consider discussing alternative treatments like corticosteroids, physical therapy, or surgical interventions, especially if you’re seeking long-term relief or have not responded well to other non-invasive therapies.

Conclusion

Euflexxa can be a helpful treatment for reducing shoulder pain caused by osteoarthritis. It mimics natural joint fluid to improve movement and alleviate discomfort. Many patients report positive outcomes from this treatment, experiencing enhanced mobility and less pain.

However, it’s essential to consult with your doctor before starting Euflexxa. They can assess the right option for your condition and guide you through the treatment process to ensure the best results.

FAQs

1. How does Euflexxa work for shoulder osteoarthritis?

Euflexxa mimics the body’s natural synovial fluid, reducing friction in the shoulder joint and providing cushioning. This improves mobility and reduces pain, especially in joints with minimal inflammation.

2. How many injections of Euflexxa are needed?

Typically, a course of three injections, spaced one week apart, is recommended for shoulder osteoarthritis. The total effect is usually seen after completing the series of shots.

3. Is Euflexxa safe for everyone with shoulder osteoarthritis?

Euflexxa is generally safe but may not be suitable for patients with severe inflammation or certain medical conditions. It’s essential to consult a healthcare professional to determine if this treatment is right for you.

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References

Floyd SB, Chapman CG, Shanley E, et al. A comparison of one-year treatment utilization for shoulder osteoarthritis patients initiating care with non-orthopaedic physicians and orthopaedic specialists. BMC Musculoskeletal Disorders. 2018;19(1). doi:10.1186/s12891-018-2268-3

Chillemi C, Franceschini V. Shoulder Osteoarthritis. Arthritis. 2013;2013:1-7. doi:https://doi.org/10.1155/2013/370231