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Polynucleotides
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Last Updated On February 4, 2025

Polynucleotides Aftercare – Essential Post-Treatment Guidelines

Jan 28, 2025

Collagen is a key protein responsible for maintaining skin structure and elasticity, but its production naturally declines with age, leading to wrinkles and sagging. Polynucleotide treatments help counteract this process by stimulating collagen production, enhancing skin firmness, and promoting overall skin regeneration.

While these treatments offer impressive benefits, proper aftercare is essential to maximize results and ensure a smooth recovery. Following the right post-treatment guidelines can help reduce temporary side effects like redness or swelling while optimizing skin hydration, elasticity, and long-term rejuvenation.

In this article, we will explore the importance of polynucleotide aftercare and detail expert-recommended steps to support healing and enhance the effectiveness of your treatment.

Key Takeaways

  • Avoid direct sun exposure or tanning beds for at least a week to prevent irritation and pigmentation issues. If sun exposure is unavoidable, apply a broad-spectrum sunscreen to protect the skin.
  • Refrain from touching or massaging the treated area for 24-48 hours to allow the product to absorb fully and minimize irritation.
  • Keep your skin well-hydrated by drinking plenty of water and using a gentle, fragrance-free moisturizer to support healing and maintain elasticity.
  • Avoid exfoliating or harsh skincare products, such as retinoids and AHAs/BHAs, for at least a week to prevent sensitivity and irritation.
  • Follow any additional advice provided by your practitioner and attend scheduled follow-up appointments to monitor progress and optimize results.
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Post-Treatment Guidelines

Following proper aftercare is essential to achieving the best results from your polynucleotide treatment. The two most critical steps are protecting the treated area from sun exposure and keeping it clean to support healing and minimize side effects.

looking young
  • Avoid Sun Exposure for Two Weeks: The skin is more sensitive after treatment, making it vulnerable to pigmentation changes and UV damage. Stay out of direct sunlight, avoid sunbeds and tanning, and use a broad-spectrum sunscreen (SPF 30 or higher) if exposure is unavoidable.
  • Keep the Treated Area Clean: Gently cleanse the skin with mild, non-irritating products to prevent infection and aid recovery. Avoid scrubbing, harsh chemicals, or alcohol-based products, which can cause irritation.
  • Minimize Contact: Refrain from touching, rubbing, or applying pressure to the treated area to reduce the risk of introducing bacteria and potential polynucleotides side effects.

By following these simple guidelines, you can help protect your skin, promote healing, and achieve long-lasting, optimal treatment results.

Hydration and Rest

Proper hydration and rest support the healing process after a polynucleotide injection. These key steps help enhance recovery, reduce inflammation, and maximize treatment effectiveness.

  • Stay Hydrated: Drinking plenty of water helps maintain skin elasticity, promote cell regeneration, and reduce swelling. Proper hydration also ensures the treatment is fully absorbed and delivers optimal results.
  • Get Enough Rest: Allowing your body time to recover helps the skin respond effectively to treatment. Avoid strenuous activities for at least 24-48 hours to prevent unnecessary strain and irritation.
  • Follow Aftercare Instructions: Adhering to your practitioner’s guidelines helps minimize complications, promote faster healing, and ensure long-lasting results.

By prioritizing hydration, rest, and proper aftercare, you can support the healing process and achieve the best possible outcome from your treatment.

Post-Treatment Follow-up

Scheduling follow-up visits after polynucleotide treatment is essential to assess progress and identify potential complications. Typically, follow-up appointments should occur 2 to 4 weeks post-treatment, though the exact timing may vary based on the type of treatment and area treated. During these visits, your healthcare provider will evaluate the effectiveness of the treatment and check for any adverse reactions.

It’s equally important to monitor the treated area yourself. Pay attention to any changes, such as persistent redness, swelling, or discomfort. Tracking these signs can provide valuable information for your healthcare provider, helping them adjust the treatment plan to enhance results. Regularly documenting your healing process will also ensure any gradual improvements are noted and appropriately addressed.

How to Maximize Treatment Results

Proper aftercare is critical for maximizing the effectiveness of your polynucleotide treatment. Following the correct post-treatment guidelines helps ensure faster healing, enhances results, and minimizes potential complications. 

preparing the injection
  • Use Sun Protection: Protect the treated area from direct sunlight and use broad-spectrum sunscreen.
  • Use Recommended Products: Apply any prescribed products or medications as directed by your provider.
  • Adopt a Gentle Skincare Routine: Use hydrating and gentle products that promote skin regeneration.
  • Avoid Harsh Active Ingredients: Do not use retinoids, glycolic acid, or Vitamin C until your provider clears you to resume.
  • Maintain a Balanced Diet: Focus on foods rich in vitamins A, C, and E to support skin health.
  • Exercise Regularly: Physical activity promotes circulation and healing.
  • Ensure Proper Sleep: Sleep is crucial for recovery and optimal healing.
  • Manage Stress: Minimize stress to improve overall healing and well-being.

Staying consistent with your aftercare routine will help you achieve long-lasting benefits and maintain the improvements for months or even years.

Conclusion

Proper aftercare is crucial for the success of your polynucleotide treatment. Protect the treated area from the sun, keep it clean, stay hydrated, and attend follow-up visits. Adhere to post-treatment guidelines, rest, and maintain a healthy lifestyle to support healing and maximize results. By following these steps, you can ensure the best possible outcomes and enjoy the benefits of the treatment for months or years.

FAQs

1. How do polynucleotides work in treatments? 

Polynucleotides stimulate tissue repair by promoting cell regeneration, enhancing collagen production, and improving skin elasticity. They are commonly used in aesthetic treatments like skin rejuvenation and hair restoration.

2. How many sessions of polynucleotide treatment are needed for cosmetic purposes? 

For cosmetic treatments, 2-4 sessions are typically recommended, spaced 2 to 4 weeks apart.

3. Are polynucleotides effective in anti-aging treatments? 

Yes, polynucleotides are highly effective in anti-aging treatments. They work by stimulating the skin’s repair mechanisms, improving skin texture, reducing wrinkles, and enhancing collagen production, leading to a youthful appearance.

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References

Cleveland Clinic. Collagen: What It is, Types, Function & Benefits. Cleveland Clinic. Published 2022. https://my.clevelandclinic.org/health/articles/23089-collagen 
Skin Boosters Are the New Injectable Everyone Will Be Talking About This Fall. Harper’s BAZAAR. Published May 31, 2023. https://www.harpersbazaar.com/beauty/skin-care/a44004377/skin-boosters-injectables-explained/