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Depo Provera
Depo Provera Generic Name – What You Need to Know
Feb 6, 2025
Generic contraceptives play a vital role in family planning, providing affordable and accessible birth control options for individuals worldwide. Among these, Depo Provera, a widely used injectable contraceptive, stands out for its effectiveness and convenience.
While many recognize Depo Provera by its brand name, its generic version offers the same active ingredient—medroxyprogesterone acetate—at a potentially lower cost. Understanding the generic name, benefits, and potential drawbacks can help individuals make informed choices about their contraceptive options.
In this article, we’ll explain everything you need to know about Depo Provera’s generic name, including its effectiveness, availability, and key considerations for those seeking a reliable, long-term birth control solution.
Key Takeaways
- Depo Provera’s generic name is medroxyprogesterone acetate, a progestin-based contraceptive that prevents pregnancy by stopping ovulation.
- A single injection provides up to three months of pregnancy prevention, offering a long-term, low-maintenance birth control option.
- Medroxyprogesterone acetate is a lab-made version of progesterone, mimicking the natural hormone’s effects in the body.
- The generic version is just as effective as the brand-name Depo Provera but may be more affordable.
- Consult a healthcare provider to determine if this birth control method is right for you.
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Generic Name: Medroxyprogesterone Acetate
Medroxyprogesterone acetate, the generic name for Depo Provera, is a synthetic form of progesterone commonly used in birth control injections. It prevents pregnancy by stopping ovulation and thickening cervical mucus, making it more difficult for sperm to reach an egg.
Beyond contraception, medroxyprogesterone acetate is also used to treat conditions like endometriosis and abnormal uterine bleeding. The generic version contains the same active ingredient as the brand-name Depo Provera, providing identical effectiveness and safety at a lower cost.
Active Ingredient and Mechanism
Depo Provera’s active ingredient, medroxyprogesterone acetate, copies the hormone progesterone to prevent pregnancy. When injected, it suppresses ovulation, meaning the ovaries do not release eggs. As previously mentioned, it also thickens the cervical mucus to create a barrier that prevents sperm from interacting with an egg.
Medroxyprogesterone acetate is typically administered as an injection once every three months, making it a highly effective, long-acting form of contraception.
Alternative Brand Names
Medroxyprogesterone acetate is marketed under several brand names aside from Depo Provera. Some of the most common alternatives include:

- Depo-subQ Provera 104: A subcutaneous injection with the same active ingredient but in a lower volume.
- Provera: An oral tablet form used for various hormonal treatments.
- Depo Provera CI: Another form specifically designed for contraception
- Amen: Used for various hormonal treatments, including contraception and hormone replacement therapy.
- Curretab: Oral tablet form of medroxyprogesterone acetate used to treat conditions like abnormal uterine bleeding, amenorrhea (absence of menstrual periods), and as part of hormone replacement therapy
Similarities and Differences Between Brand-Name and Generic Versions
Both brand-name Depo Provera and its generic counterpart, medroxyprogesterone acetate, contain the same active ingredient and work through the same mechanism to prevent pregnancy. However, there are a few key differences to consider:
- Cost: The generic version is typically more affordable, making it a cost-effective alternative for many patients.
- Packaging & Appearance: While the generic version may have different packaging or a slightly different appearance, it is just as effective and reliable as the brand-name product.
- Regulatory Approval: Generic drugs undergo strict testing and regulatory approval to ensure they match the safety, quality, and effectiveness of their brand-name counterparts.
Cost-Effectiveness of Generic Depo Provera
A key advantage of generic Depo Provera is its affordability. Without the high development costs of brand-name drugs, it’s significantly cheaper. This makes it a practical option for those without insurance or with high medication expenses.
Despite the lower price, generic medroxyprogesterone acetate provides the same effectiveness and safety as the brand-name version. For those seeking reliable birth control, the generic option offers a cost-effective solution without sacrificing quality or performance. Always consult a healthcare provider before switching.
Regulatory Considerations
Depo Provera’s effectiveness, along with that of its generic version, medroxyprogesterone acetate, is regulated by the FDA (U.S. Food and Drug Administration) to ensure both meet strict safety, efficacy, and manufacturing quality standards. Before approval, the FDA reviews clinical trials and data to confirm that generics are bioequivalent to their brand-name counterparts—meaning they must release the same amount of active ingredient at the same rate.

This rigorous oversight ensures that patients receive the same level of pregnancy prevention and therapeutic benefits from the generic version as they would from brand-name Depo Provera. Because both versions maintain the same high standards, healthcare providers often recommend the more affordable generic option when appropriate.
Potential Differences in Quality or Formulation
While generic Depo Provera contains the same active ingredient as the brand-name version, minor formulation differences may exist. These variations typically do not impact effectiveness but can influence tolerability for some individuals. Their possible differences include:
- Inactive Ingredients: Generic versions may use different preservatives, stabilizers, or binding agents.
- Manufacturing Process: Variations in production methods can cause slight differences in texture or absorption rate.
- Storage and Shelf Life: Some generic formulations may have different expiration dates or storage requirements.
- Patient Sensitivity: Rarely, individuals may react to a specific inactive ingredient in a generic version.
If you experience side effects or concerns, consult your healthcare provider to determine your best option.
Conclusion
Medroxyprogesterone acetate, the generic version of Depo Provera, offers a cost-effective and reliable contraceptive option. It prevents pregnancy by stopping ovulation and thickening cervical mucus, providing the same level of protection as the brand-name version.
Since it meets the same rigorous FDA safety and effectiveness standards, patients can trust that the generic option delivers equally reliable birth control at a more affordable price. For those looking for a budget-friendly, long-term contraceptive solution, medroxyprogesterone acetate remains a practical and accessible choice.
FAQs
1. How long does Depo Provera last?
Depo Provera provides birth control for up to 3 months with each injection. After that, a follow-up shot is required to maintain effectiveness.
2. Are there any side effects of Depo Provera?
Common side effects include changes in menstrual periods, weight gain, headaches, and mood changes. It’s important to discuss any side effects with your doctor.
3. Can Depo Provera affect fertility?
Fertility typically returns after a few months once the medication is stopped. However, some individuals may experience a delay in getting pregnant after discontinuing Depo Provera.
4. How effective is Depo Provera?
When used correctly, Depo Provera is more than 99% effective in preventing pregnancy.
References
Fiffick AN, Iyer TK, Cochran T, Batur P. Update on current contraceptive options: A case-based discussion of efficacy, eligibility, and use. Cleveland Clinic Journal of Medicine. 2023;90(3):181-190. doi:https://doi.org/10.3949/ccjm.90a.22075
World Health Organization. Family planning/contraception methods. Published September 5, 2023. https://www.who.int/news-room/fact-sheets/detail/family-planning-contraception
OHCHR. Women’s autonomy, equality and reproductive health. OHCHR. https://www.ohchr.org/en/special-procedures/wg-women-and-girls/womens-autonomy-equality-and-reproductive-health
Depo Provera (Medroxyprogesterone): Uses, Dosage, Side Effects, Interactions, Warning. RxList. https://www.rxlist.com/Depo Provera-drug.htm