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Ejal 40
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Last Updated On February 23, 2025

Ejal 40 vs Profhilo – A Comparison of Two Skin Rejuvenation Treatments

Feb 11, 2025

Aging is a natural process, but its visible effects—such as fine lines, wrinkles, and decreased skin elasticity—can be managed with the right treatments. Hydration plays a crucial role in maintaining youthful, healthy skin, as well-moisturized skin is more resilient and better equipped to combat aging.

Ejal 40 and Profhilo are two cutting-edge injectable treatments designed to rejuvenate the skin. While both utilize hyaluronic acid to improve hydration and elasticity, they work in distinct ways. Ejal 40 primarily focuses on deep hydration and collagen stimulation, whereas Profhilo offers bio-remodeling effects that tighten and firm the skin. Understanding their differences can help individuals choose the best option for their specific skin concerns.

This article will provide a detailed comparison of Ejal 40 vs Profhilo, examining their mechanisms, benefits, longevity, and ideal candidates to help readers make an informed decision.

Key Takeaways

  • Ejal 40 and Profhilo use hyaluronic acid to improve skin hydration and elasticity, but their composition and application differ.
  • Ejal 40 has a lower molecular weight, making it suitable for targeted skin repair and collagen stimulation.
  • Profhilo has a higher hyaluronic acid concentration, allowing for deep hydration and a subtle lifting effect.
  • Injection techniques vary, with Ejal 40 utilizing multiple microinjections, while Profhilo follows the BAP (Bio Aesthetic Points) method.
  • Results last 4-6 months for both treatments, but patient-specific factors influence longevity.
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Introduction to Ejal 40 and Profhilo

Ejal 40 and Profhilo are both advanced injectable treatments that enhance skin hydration, elasticity, and overall rejuvenation. While they share hyaluronic acid (HA) as a key ingredient, their mechanisms of action and targeted benefits differ significantly.

  • Ejal 40: Delivers intensive hydration while stimulating collagen production, making it ideal for skin revitalization and repair
  • Profhilo: Acts as a bio-remodeling treatment, improving skin firmness and tightening lax skin by encouraging natural tissue remodeling.

Choosing between these two treatments depends on individual skin concerns and desired outcomes. Those seeking enhanced hydration and repair may prefer Ejal 40, while individuals looking for skin tightening and long-term structural improvement might find Profhilo more suitable. 

Composition and Hyaluronic Acid Concentration in Ejal 40 and Profhilo

Ejal 40 and Profhilo differ significantly in their hyaluronic acid concentration and composition, which affects their performance and treatment outcomes.

  • Ejal 40: Contains 40 mg of hyaluronic acid in a 2 mL syringe. It is a medium-molecular-weight HA designed to enhance hydration, stimulate collagen, and support extracellular matrix repair.
  • Profhilo: Contains 64 mg of pure hyaluronic acid in a 2 mL syringe, making it among the highest-concentration HA injectables available. It is a unique hybrid of high- and low-molecular-weight HA that provides hydration and mild skin tightening.

Mechanisms of Action: Ejal 40 Versus Profhilo

Ejal 40 effectively stimulates fibroblast activity, which in turn boosts collagen production. This aids in improving skin hydration and elasticity. It also supports the restoration of the extracellular matrix, enhancing the overall skin structure.

doctor in the clinic

Meanwhile, Profhilo treatment features a unique hybrid complex of hyaluronic acid. This combination allows it to spread more uniformly through the skin layers, providing deep hydration. Additionally, it aids in bio-remodeling by stimulating the production of collagen and elastin, which contributes to skin firmness and elasticity.

Differences in Molecular Weight and Impact on Treatment Outcomes

Molecular weight significantly influences how hyaluronic acid (HA) functions in the skin. Ejal 40 contains medium-molecular-weight HA, which promotes gradual skin renewal, making it ideal for repairing damage, improving texture, and reducing fine lines. Profhilo, on the other hand, blends high and low-molecular-weight HA, allowing for deep hydration and a subtle lifting effect, making it more effective for skin laxity concerns. 

These differences impact how each treatment integrates into the skin, affecting absorption rate, longevity, and overall aesthetic results, helping practitioners select the best option based on individual skin needs.

Injection Techniques: Ejal 40 Compared to Profhilo

The injection technique is crucial in how these treatments distribute hyaluronic acid, impacting effectiveness and results.

  • Ejal 40 is administered using microinjections across the treatment area, ensuring precise delivery of HA to targeted skin layers.
  • Profhilo follows the BAP (Bio Aesthetic Points) technique, requiring five injection points on each side of the face for optimal diffusion and even hydration.

While Ejal 40 offers more localized collagen stimulation, Profhilo provides a more generalized skin-enhancing effect with fewer injection sites.

Patient Selection Criteria for Ejal 40 and Profhilo

Choosing the right candidates ensures safe, effective results. Both treatments improve skin hydration and elasticity, but suitability depends on individual needs.

Ejal 40 is best for those who:

  • Have early signs of aging and mild laxity
  • Experience dehydrated or dull skin
  • Seek collagen stimulation without added volume

Profhilo is ideal for individuals who:

  • Have moderate skin laxity and crepey texture
  • Need deep hydration and bio-remodeling
  • Want overall skin rejuvenation

Both treatments are unsuitable for individuals with active infections, autoimmune diseases, severe allergies, or pregnancy. A professional consultation ensures the right choice.

Efficacy in Addressing Various Signs of Aging: Ejal 40 vs. Profhilo

Ejal 40 and Profhilo both enhance skin quality, but they address aging concerns in distinct ways. Ejal 40 targets localized issues such as fine lines, uneven texture, and mild skin damage by stimulating collagen production in specific areas. This treatment gradually improves skin tone and elasticity, making it ideal for targeted rejuvenation.

sexy woman

On the other hand, Profhilo is known for its high spreadability, delivering deep hydration while addressing overall skin laxity. It is particularly effective for volume loss and crepey skin, providing a natural lifting and firming effect.

Duration of Results: Comparing Ejal 40 and Profhilo

Ejal 40 results typically last 3–6 months, with gradual skin renewal and collagen stimulation requiring maintenance sessions. Factors like skin type and lifestyle impact longevity. Profhilo offers longer-lasting hydration and firmness, with visible effects for 6–9 months. Its hybrid HA formulation integrates deeply, enhancing overall skin quality. 

While both treatments need periodic upkeep, Profhilo generally maintains skin elasticity and hydration for a longer period, making it ideal for those seeking extended anti-aging benefits.

Potential Side Effects and Contraindications of Ejal 40 and Profhilo

While Ejal 40 and Profhilo are effective skin boosters, they may cause temporary side effects. Understanding potential reactions helps ensure a safe treatment experience and proper aftercare for optimal results. Common side effects include:

  • Mild swelling, redness, or bruising
  • Tenderness or slight discomfort
  • Small lumps at the Ejal 40 injection points
  • Itching or skin irritation

Less common risks include infection or allergic reactions. Contraindications for these treatments include:

  • Allergy to hyaluronic acid
  • Active skin infections or inflammation
  • Autoimmune disorders
  • Pregnancy or breastfeeding
  • Use of blood thinners or clotting disorders
  • History of severe allergic reactions

To minimize risks, consult a qualified provider before treatment. Proper aftercare and professional guidance help ensure safe and effective results.

Guidelines for Choosing Between Ejal 40 and Profhilo Based on Patient Needs

Selecting between Ejal 40 and Profhilo depends on individual skin concerns and treatment goals. Ejal 40 is best for those seeking targeted skin repair, fine line reduction, and improved texture, as it works in specific areas. Profhilo is ideal for patients experiencing overall skin laxity, dryness, or loss of firmness, offering a more uniform bio-remodeling effect. 

Those preferring fewer injection points may opt for Profhilo, while individuals needing precise collagen stimulation may benefit more from Ejal 40. A professional assessment helps determine the best approach, ensuring the treatment aligns with the patient’s skin condition and aesthetic goals.

Conclusion

Ejal 40 and Profhilo both deliver exceptional skin rejuvenation, yet they cater to distinct needs. Ejal 40 excels in targeted skin repair and bio-revitalization, making it ideal for addressing fine lines, texture irregularities, and localized collagen stimulation. Meanwhile, Profhilo is designed for deep hydration and subtle lifting, improving overall skin laxity and elasticity with a more widespread effect.

Choosing between these treatments depends on individual goals—Ejal 40 for precise skin renewal and Profhilo for comprehensive skin remodeling. Understanding their differences allows patients and practitioners to select the most effective option for achieving long-lasting, natural-looking skin rejuvenation.

FAQs

1. How many sessions of Ejal 40 are needed? 

Typically, 2-3 sessions spaced 2-4 weeks apart are recommended for optimal results.

2. Can Ejal 40 be combined with other treatments? 

It can be combined with microneedling, PRP, and other skin rejuvenation treatments for enhanced effects.

3. Is Ejal 40 painful? 

Most patients experience mild discomfort, but numbing cream can reduce pain.

4. When will I see results from Ejal 40? 

Initial improvements are visible within a few weeks, with full effects appearing after multiple sessions.

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References

Link between hydration and aging. National Institutes of Health (NIH). Published January 24, 2023. https://www.nih.gov/news-events/nih-research-matters/link-between-hydration-aging

Bizot V, Cestone E, Michelotti A, Nobile V. Improving skin hydration and age-related symptoms by oral administration of wheat glucosylceramides and digalactosyl diglycerides: a human clinical study. Cosmetics. 2017;4(4):37. doi:10.3390/cosmetics4040037

Yi K, Winayanuwattikun W, Kim S, et al. Skin boosters: Definitions and varied classifications. Skin Research and Technology. 2024;30(3). doi:10.1111/srt.13627