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Profhilo
What Is Profhilo?
May 17, 2025
Did you know that skin aging isn’t just about wrinkles? Factors like loss of hydration, decreased elasticity, and declining skin quality play a huge role in how youthful your complexion appears. Enter bioremodeling injectables, powered by hyaluronic acid, which work by stimulating collagen and elastin production to restore the skin’s natural structure and function. Unlike traditional fillers that simply add volume, these treatments deliver a more natural, radiant glow by repairing skin from within.
At the forefront of this innovation is Profhilo — a unique formulation that spreads evenly under the skin to stimulate repair processes rather than just plumping. The result is a subtle yet noticeable rejuvenation that brings back the skin’s smoothness and firmness.
But what exactly makes Profhilo different from other treatments, and why is it gaining so much attention? This article will explore the science behind Profhilo, its key benefits, and its growing role in modern skin rejuvenation.
Key Takeaways
- Profhilo is a hyaluronic acid-based injectable that enhances skin hydration, firmness, and quality.
- It uses NAHYCO® hybrid technology, combining high- and low-molecular-weight HA without chemical cross-linking.
- Profhilo spreads evenly beneath the skin to stimulate collagen and elastin production, improving skin tone and texture.
- Common treatment areas include the face, neck, décolletage, and hands for visible skin rejuvenation.
- The treatment protocol usually includes two sessions spaced four weeks apart with minimal discomfort or downtime.
- Profhilo is ideal for patients with mild to moderate skin laxity who want subtle, natural-looking improvement.
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Profhilo’s Composition and Mechanism
Profhilo consists of 64 mg of pure hyaluronic acid (HA)—equally split between 32 mg of high molecular weight and 32 mg of low molecular weight HA—stabilized using the patented NAHYCO® technology. Unlike many dermal fillers that rely on chemical cross-linking agents, this thermal stabilization technique preserves the natural properties of hyaluronic acid while maintaining high biocompatibility and minimizing the risk of adverse reactions.
Once injected, Profhilo seamlessly flows through the skin’s layers, binding large amounts of water molecules to deliver deep hydration. Moreover, it acts as a bio-stimulator, encouraging fibroblasts to produce both collagen and elastin, essential proteins responsible for skin firmness and elasticity. This dual-action mechanism makes Profhilo particularly well-suited for patients seeking effective anti-aging results without the volume increase seen with traditional fillers.
Clinical Applications of Profhilo
Profhilo has significantly transformed the landscape of aesthetic medicine by introducing a novel approach to skin bio-remodeling. Rather than simply adding volume, it deeply hydrates and stimulates the skin’s natural regenerative pathways, resulting in more natural rejuvenation. Its high concentration of pure hyaluronic acid enables effective treatment across various areas, enhancing skin texture, firmness, and elasticity.
Profhilo’s versatility extends beyond the face and is increasingly popular for improving multiple regions, including:
- Face: Reduces fine lines, enhances hydration, and improves overall skin quality.
- Neck: Addresses skin laxity and crepey texture.
- Hands: Restores volume and smoothness.
- Décolletage: Improves elasticity and minimizes wrinkles.
- Arms & Knees: Helps tighten and hydrate aging skin.
Patient Selection Criteria for Profhilo
Selecting the right patients for Profhilo is essential to ensure effective, natural-looking results and long-term satisfaction with this skin-rejuvenating, non-volumizing hyaluronic acid treatment. Ideal candidates typically meet the following criteria:
- Adults over the age of 30 experiencing early signs of aging or skin dehydration
- Patients with mild to moderate skin laxity rather than deep wrinkles or sagging
- Individuals seeking non-surgical skin rejuvenation without facial volume enhancement
- Patients looking for a preventive anti-aging treatment with natural results
- Those with no history of hypersensitivity to hyaluronic acid or severe autoimmune conditions
Patients presenting with more advanced aging or requiring substantial volume restoration may need combination therapies involving dermal fillers or energy-based devices. A thorough consultation is essential to determine whether Profhilo alone will suffice or should complement a broader treatment plan.
Treatment Protocol and Expected Outcomes
The typical Profhilo treatment protocol involves two sessions spaced approximately four weeks apart. During each session, small quantities of Profhilo are injected using the BAP (Bio Aesthetic Points) technique, which targets key anatomical points to optimize product diffusion and efficacy.
Treatment Schedule
- Session 1: Baseline injection at five key facial points per side (or specific zones on neck/hands).
- Session 2: Second round of injections, four weeks later, to boost and sustain results.
- Maintenance: Optional touch-up every six months for continued skin quality improvement.
Patients usually notice smoother, firmer, and more hydrated skin within 2 to 4 weeks following the second session, with full results visible around 6 to 8 weeks. These results typically last up to six months, influenced by factors like age, skin condition, and lifestyle.
Profhilo side effects are generally mild and temporary, including common reactions such as swelling, redness, or bruising at the injection sites. Downtime is minimal, making it a convenient option for patients seeking effective rejuvenation with little disruption to their daily lives.
Conclusion
Profhilo offers a groundbreaking approach to skin rejuvenation by focusing on improving skin quality rather than simply filling wrinkles or adding volume. Its advanced formulation of high-purity hyaluronic acid works at a cellular level to boost hydration, firmness, and elasticity, providing subtle yet effective results.
With a streamlined treatment protocol, minimal recovery time, and excellent safety profile, Profhilo is ideally suited for individuals beginning to notice early signs of aging. By carefully selecting patients and adhering to a structured treatment plan, practitioners can deliver significant, long-lasting skin revitalization without resorting to invasive procedures.
FAQs
1. How is Profhilo different from dermal fillers?
Profhilo spreads evenly under the skin to improve hydration and elasticity, while fillers are designed to add volume and structure.
2. Is Profhilo safe?
It contains pure hyaluronic acid without chemical cross-linkers, making it highly biocompatible and well-tolerated.
3. How long does the procedure take?
Each session typically takes 15–30 minutes, depending on the treatment area.
4. When will I see results?
Initial improvements may be visible after the first session, with full results developing 4–6 weeks after the second session.
5. How long do results last?
Results typically last up to six months. Maintenance sessions every 6–9 months are recommended for sustained benefits.
6. Can Profhilo be combined with other treatments?
Yes, it pairs well with dermal fillers, laser treatments, and skin tightening procedures for comprehensive anti-aging strategies.
7. Are there any side effects?
Most side effects are mild and temporary, including redness, swelling, or bruising at the injection sites.
References
Bolke L, Schlippe G, Gerß J, Voss W. A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients. 2019;11(10):2494. doi:https://doi.org/10.3390/nu11102494
Yi K, Waranaree Winayanuwattikun, Kim S, et al. Skin boosters: Definitions and varied classifications. Skin research and technology. 2024;30(3). doi:https://doi.org/10.1111/srt.13627