What is Prilocaine?
Prilocaine is an amino amide type of local anaesthetic with a fast onset of action. It is pharmacologically similar to lidocaine and both can be combined for topical application (Emla cream) prior to a dermal filler injection. Although both are equally safe and effective anaesthetics, prilocaine’s onset of action is slower than lidocaine. However, the former is excreted more rapidly and has lower cardiotoxicity. Lidocaine is widely used in the US, while European countries seem to prefer Prilocaine.
Mechanism of Action
Amide-type local anaesthetics like prilocaine and lidocaine relieve pain by interfering with nerve excitation and conduction. It works by blocking sodium (Na+) current through direct interaction with voltage-gated Na+ channels. The injectable form of prilocaine is often used in dentistry, while a combination of lidocaine and prilocaine is also formulated in topical preparation for dermal anaesthesia. It is rapidly metabolised in the liver a ...
What is cervical dystonia?
Cervical dystonia (CD) is the most common form of focal dystonia characterised by sustained or intermittent muscle contraction that leads to abnormal movements and posture. There is no known cure for CD, but multiple treatments are available to relieve symptoms. The choice of treatment depends on the cause of the dystonia and the muscles involved.
Botox injections for cervical dystonia
Botox is a prescription medication containing botulinum neurotoxin A that is injected into muscles to treat cervical dystonia in adults. Other ingredients include human albumin and sodium chloride. The safety of Botox for this indication has not been established for pregnant and lactating patients. Patients who are allergic to other botulinum toxin type A products (Xeomin, Myobloc, and Dysport) should not receive this treatment. Patients with existing neuromuscular conditions such as Lou Gehrig’s disease, amyotrophic lateral sclerosis, myasthenia gra ...
What is Botox?
Botox is widely known for treating a growing number of cosmetic and clinical indications. Botox dominated the beauty industry as a minimally invasive procedure for treating lines and wrinkles. The approval of Botox through various regulatory agents has also paved the way for its off-label usage. The effectiveness of this neurotoxin for excessive sweating (hyperhidrosis) led some doctors to test its effects on the scalp as well. Dermatologists who are offering Botox for hair in their clinics claim to give the following benefits:
Reducing sweating in the scalp;
Possibly stimulating new hair growth;
Preventing hair loss.
How Botox for hair treatment works
Simply put, the absence of sweat in a Botox-treated scalp helps preserve hairstyles longer. Most patients who will seek this treatment want to keep their hairs in top shape even while working out. Those with a naturally oily scalp may prefer longer days in between hair washes. Other doctors may also recommend thi ...