What is Stylage?
Stylage is a brand of injectable dermal fillers that are designed and manufactured by Vivacy Laboratories, a renowned French pharmaceutical company. The fillers are made of nonanimal-based hyaluronic acid molecules. The molecules are extracted through biofermentation and highly purified before they are cross-linked with a patented reticulating technology, IPN-Like Technology. The resulting gel is biodegradable and extremely viscoelastic with a monophasic texture. The fillers are unique as they are incorporated with antioxidants mannitol or sorbitol to not only preserve the physio-chemical properties of the filler gel but also to maintain good skin health by scavenging any harmful free radicals. After many years of research and development, the Stylage brand boasts a wide collection of fillers that can be used to address many aesthetic issues—from correcting simple skin dullness to volumising sunken facial regions. Some of the fillers are available with lidocaine to better manage pain and discomfort during the injection session.
What is Juvederm?
Juvederm is a collection of cross-linked hyaluronic acid soft tissue fillers that are formulated and produced by Allergan, a multinational pharmaceutical company specialising in manufacturing branded medical products. The hyaluronic acid molecules are produced synthetically and aseptically by fermenting bacterial cultures before they are purified to be free from any potentially harmful impurities. The hyaluronic acid particles are then cross-linked with each other using either Vycross™ or Hyalacross™ Technologies. The resulting bioresorbable gel is of monophasic texture. Juvederm fillers be used to correct numerous skin defects such as dehydration and facial fat atrophy. Some of the fillers are also available with fast-acting lidocaine to ensure utmost comfort during treatment session.
Difference between Stylage vs Juvederm
The major difference is that Stylage fillers are integrated with antioxidants. These skin-protective components help to preserve the action of the filler material once implanted into the skin by ensuring that the injected areas are not damaged by free radicals. Besides the integration of antioxidants, another difference is the cross-linking technologies employed to process the 2 brands. IPN-Like Technology cross-links the hyaluronic acid molecules together with minimal usage of the chemical reticulating agent, 1,4-butanediol diglycidyl ether (BDDE). Vycross Technology cross-links 90% (majority) low molecular weight and 10% (minority) high molecular weight hyaluronic acid. In comparison, Hyalacross Technology produces fillers with a smooth and less granular consistency.