Name: BOTOX®.
Ingredients: Botulinum toxin type A (from Clostridium botulinum).
Size: One vial contains 100 Allergan Units powder for solution for injection.
Manufacturer: Allergan, Inc.
Origin: Europe.
Also Included: Package leaflet only.
Storage: Keep out of the reach and sight of children. Store in a refrigerator(2℃ - 8℃), or store in a freezer (at or below -5℃). After the solution is made up, immediate use of the solution is recommended; however it can be stored for up to 24 hours in a refrigerator (2℃ - 8℃).
Remarks: Sterile packaging.

What is Botox 100 Units?


Botox (BTX) is a muscle relaxant that may be used to treat a variety of physical ailments. Through botulinum toxin type A, its active constituent, BTX blocks nerve activity in the injection site to reduce excessive muscular contraction. BTX may be used to treat a vast array of conditions, including facial wrinkles and folds, chronic migraines, and urinary incontinence.

Allergan, a global pharmaceutical company, oversees the manufacturing and distribution of Botox. An industry leader in Open Science, Allergan focuses on the development and identification of innovative medicinal products and services.

Each package of BTX 100U contains 1 vial filled with 100 units of BTX. Botox should be stored between 2 and 8°C and kept out of the reach of children.


What is it used for?


Botox may be used in a variety of medical conditions to relax the muscles. Its main uses include:

  1. The treatment of overactive bladder (OAB);
  2. The treatment of urinary incontinence caused by detrusor overactivity;
  3. The prevention of headaches in adults with chronic migraines;
  4. The treatment of adult spasticity;
  5. The reduction of abnormal head position and neck pain in cervical dystonia patients;
  6. The treatment of hyperhidrosis (excessive sweating);
  7. The treatment of blepharospasm and strabismus in patients under 12 years of age;
  8. And the cosmetic reduction of fine lines, folds, and wrinkles on the face.


How does botulinum toxin work?


Botox relaxes the muscles by temporarily blocking the release of acetylcholine, a neurotransmitter that controls the communication of impulses between the nerves and the muscles. By inhibiting the release of this chemical, neuromuscular communications are cut off, hindering these impulses and bringing movement to a halt.

In this formulation, Clostridium botulinum (the source of botulinum toxin type A) has been purified to nullify the existence of complexing proteins. This process increases Botox’s overall effectiveness: complexing proteins may trigger the formation of antibodies, which are known to weaken the potency of cosmetic and medical treatments.

When injected into the sweat glands, Botox reduces sweat production, effectively treating hyperhidrosis. To prevent overactivity in the bladder or urinary incontinence, BTX may be injected into the bladder wall to reduce the muscular contractions that lead to leakage. It may also be used to relieve muscular spasms, control severe migraines, and correct foot deformities in paediatric patients with cerebral palsy. Additionally, BTX may be used to temporarily correct facial lines and wrinkles by relaxing the facial muscles.


How to inject BTX


Only certified, trained medical practitioners may carry out Botox injections. These individuals must also have specialised knowledge in botulinum toxin treatments, as well as an expert understanding of human anatomy and injection techniques.

Before beginning the injection process, reconstitute the supplied powder via aseptic clinical practice guidelines. Once reconstituted, the botulinum toxin should be clear, colourless, and free of particulate matter.

Please note that proper dosages and specific administration recommendations must be followed for each indication to be treated. Additionally, when beginning treatment with BTX, the lowest recommended dosage should be used. When treating patients for multiple medical conditions, the maximum dose should not exceed 400 units over the course of 3 months.

For the treatment of bladder dysfunction, Botox should be injected into the detrusor muscle with via a flexible or rigid cystoscope. The bladder should be filed with saline solution to attain appropriate visualisation for the injections. During the injection process, the needle is to be inserted into the detrusor muscle at a depth of 2mm. Once the appointment is complete, patients should demonstrate their ability to void the treated area.

When treating chronic migraine, 155 units should be injected into the muscles of the head and neck using a 30G½” needle. Injections should be done bilaterally (with the exception of those in the procerus muscle).

Patients seeking treatment for muscular spasticity should be offered tailored treatment sessions based on the location, size, and number of the muscles involved. Additionally, the severity of their spasms, any muscle weakness, or adverse reactions to Botox should be taken into account.


How long does Botox last?


The longevity of Botox treatments is dependent on the condition being treated, as well as the age and lifestyle of the patient. In certain cases, effects may last around 24 weeks, while other BTX treatments may lose efficacy after 12 weeks. For more information, consult the information supplied in the product packaging.


Is this product safe?


Certain individuals should not be treated with Botox due to existing contraindications. Pregnant or breastfeeding individuals, as well as those with an allergy to any of Botox’s ingredients, should not be administered this solution. Those with an infection at the injection site should also avoid BTX injections.

The safety of this treatment has not been established in patients under 18 for the treatment of chronic migraines, overactive bladder, spasticity, and hyperhidrosis. Additionally, BTX has not been tested for safe use in patients under 16 for cervical dystonia, or in patients under 12 for the treatment of blepharospasm and strabismus.

BTX should be used with caution in patients with compromised respiratory function and concomitant neuromuscular disorders.


Botulinum Toxin Side Effects


Certain side effects have been found to occur with Botox injection. However, many of these are minor, and should resolve themselves shortly. If any adverse effects are noted, medical attention should be sought immediately.


Common Side Effects:


  • Muscle weakness
  • Bruising or redness at the injection site
  • Pain or inflammation at the injection site
  • Muscle stiffness
  • Headaches
  • Increased sweating
  • Symptoms of the flu


Less Common Side Effects:


  • Severe and unusual muscle weakness
  • Trouble breathing, swallowing, or talking
  • Allergy
  • Hypersensitivity
  • Nerve damage
  • Seizures


What is BTX made of?


Botox’s main active component is botulinum toxin type A, which is sourced from Clostridium botulinum bacteria. In this formulation, it is used to prevent the body from releasing a neurotransmitter called acetylcholine, which is accountable for the activation of muscles. By relaxing the areas into which it is injected, BTX may be used in a variety of ailments to treat unwanted muscular contractions.