Vials and syringes on blue background

Botulinum toxin type A is popular treatment used to reduce facial lines and wrinkles. It is also known to relieve various medical conditions, ranging from cervical dystonia to upper limb spasticity. Botox was the first botulinum toxin to be approved by regulatory agent. Dysport entered the market a few years later, and also gained approval from regulatory agents. A frequently asked question regarding botulinum toxin is the difference between Dysport and Botox. Both products contain botulinum toxin type A, but they have a few differences.

Differences Between Dysport vs Botox

Molecular size

Dysport has smaller molecules compared to Botox, which means it diffuses more and spreads out over a broader area. This can be beneficial when treating larger areas, such as the forehead.


The formula of Dysport is more diluted than Botox, so their dosage level is not interchangeable. It also means a greater number of units is needed when using Dysport than with Botox, but higher dilution doesn’t mean lesser efficacy.


Compared to Botox, Dysport diffuses more and easily spreads to a broader area when injected. When addressing large areas, Dysport may be more cost-effective because fewer injections will be necessary to target these areas. On the other hand, it may not be as effective in treating smaller areas, and risk of migration may also be higher.


There is no substantial proof of which product lasts the longest. Botulinum toxin type A injectables generally last within 3–6 months. A small study revealed that Botox may last longer than Dysport, but a larger study disputed this claim. Among 180 patients treated, both brands have shown similar duration of effects.

If your patients are looking for botulinum toxin injections, it is likely the deciding factor will be the cost. Dysport costs slightly less than Botox. Discuss the options with your patients, so they can make an informed decision about their treatment.


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