What is the Difference Between Orthovisc Vs Synvisc Injection?

What is Orthovisc?

Orthovisc is an injectable viscosupplement that is used to treat osteoarthritis of the knee. It is made of hyaluronan and comes as a 30mg/2mL pre-filled syringe, which must be prescribed to patients by a physician and administered by a medical professional in office. Orthovisc effectively relieves pain in patients suffering from osteoarthritis of the knee because it is similar to the synovial fluid that surrounds the joints, acting as a lubricant and shock absorber. While treatment with Orthovisc is proven to be safe and effective, there are some mild side effects that may occur, including:

  • Pain, stiffness, or swelling of the joint;
  • Itching, numbness, tingling;
  • Headache, dizziness;
  • Back pain;
  • Redness, swelling, pain at injection site.

What is Synvisc?

It is also a viscosupplement that can be injected into the knee joint of patients suffering from osteoarthritis. However, the difference between Orthovisc vs Synvisc is that Synvisc is made of hylan A and hylan B polymers and is also known as hylan G-F 20. Synvisc comes in a 16mg/2mL pre-filled syringe and must also be prescribed and administered by a physician. Treatment with Synvisc is also safe and effective, though there are some mild side effects that may arise, including:

  • Muscle pain;
  • Numbness, tingling;
  • Fever, chills;
  • Itching or skin irritation around the knee;
  • Warmth, stiffness, swelling, pain, or puffiness at injection site.

Difference between Orthovisc Vs Synvisc injection

The biggest difference between Orthovisc vs Synvisc is in the dosage. The quantity of the active ingredient differs between the products, with Orthovisc containing 30mg/2mL and Synvisc containing 16mg/2mL. Treatment with each injectable typically involves one intra-articular injection with the pre-filled syringe a week for three weeks. Some patients may require a fourth injection of Orthovisc. The expected longevity of results for Orthovisc vs Synvisc is up to six months for both products.