DESIRIAL® 19mg/ml 2-1ml prefilled syringes


Active Substance(s):
Sodium hyaluronate, mannitol
Pack Size:
2-1ml prefilled syringes
Package insert, 2-27G 1/2" needles, 2-30G 1/2" needles
USD$179 179USD


What is Desirial?


As the first antioxidant, hyaluronic acid-based gel formulated for the treatment of vaginal dryness, Desirial is a unique new treatment option in women’s gynaecologic care. This injectable viscosupplement solution is non-animal and biodegradable, making it both bioavailable and safe for use.

Generally, Desirial is used to restore hydration to the vulvovaginal area. It is typically recommended for perimenopausal women—or those of reproductive age—who suffer from dehydration of the vulva. However, it may also be used to treat other health conditions, including dyspareunia, dryness, vulvodynia, irritation, discomfort, itching, and pulling sensations in the affected area.

Desirial is powered by hyaluronic acid, which is found naturally in the body’s mucous membranes. This compound can retain up to 1,000 times its weight in water, helping to hydrate and tone any tissues into which it is injected. Because hyaluronic acid has a short half-life and is soluble in water, Desirial features a cross-linked variety in order to ensure the filler’s stability. During the cross-linking process, molecules are bound together and are able to remain intact for several months. This enables Desirial to maintain its hydrating properties for long periods of time.

Desirial is designed and manufactured in France by Laboratoires Vivacy, an aesthetic and anti-aging medicine specialist that deals in the production and distribution of high-quality injectables. Founded in 2007, Vivacy was created by specialists qualified in biopolymers and injectable product technologies with more than 25 years of experience in the field.

Each package of Desirial contains 2 prefilled 1mL syringes, 2-27G½” needles, 2-30G½” needles and IPN-Like cross-linked sodium hyaluronate.


What is it used for?


Vaginal dryness is a common experience among women, and may stem from a variety of health issues, including the consumption of prescription medications and menopause. Characterized by feelings of chronic irritation, burning, and itching, this ailment leads to the drying of vaginal mucosa and the loss of elasticity. Caused by the decreased vascularization of the dermis and the degeneration of collagen and elastin fibres, this issue can seriously affect a patient’s quality of life.

Desirial offers a solution to this problem: designed to restore tone, elasticity, sensitivity, and hydration to the vulvovaginal area, this injectable filler drastically reduces vaginal discomfort. With this, hyaluronic acid is injected directly into the affected tissues for instantaneous comfort and relief.


How does this dermal filler work?


Desirial injections are meant to hydrate the vulvovaginal area by providing hyaluronic acid directly to its tissues. By providing indirect mechanical pressure on the cells that form mucosa, this procedure increases their activity. In turn, this leads to the synthesis of elastin and collagen fibres, improving the overall quality and quantity of vulvovaginal mucosa.

This dermal filler utilizes Vivacy’s patented IPN-Like Technology. This inventive feature involves the interpenetration of two monophasic, cross-linked hyaluronic acid networks, stabilizing this compound to ensure increased efficacy, tolerance, safety, and product endurance.

Desirial also features the antioxidant mannitol, which works to limit post-injection gel degradation. Mannitol scavenges free radicals generated by the penetration of the cannula or needle, protecting the hyaluronic acid molecules during the first hours after injection.


How to inject


To ensure efficient hydration of the vulva, Desirial is injected directly into the vulvovaginal tissue. Due to the sensitivity of this area, a simple local anaesthetic may be necessary to ensure a painless, more efficient treatment.

Specifically, Desirial is injected into the sides of the longitudinal axis of the labia minora or labia majora. A very fine needle (27–30G) must be used during this process, as this will allow for the product to be injected superficially.

Desirial injections must be performed by practitioners specialized in both reconstructive and functional gynaecology. Practitioners must be legally authorized to offer this service, and must have a strong anatomical knowledge of the treatment site and experience with filler injection techniques. Desirial must never be injected into the muscles or blood vessels.

Each procedure lasts about 20 minutes. Additional sessions may be required to ensure long-lasting, optimal results.


How long does this dermal filler last?


Various clinical data shows that Desirial may last anywhere from 6 months to 2 years. Of course, this may vary based on each patient’s age or medical history.


Is this product safe?


While Desirial has been exhaustively studied to determine patient safety, some individuals should abstain from this treatment. Pregnant or breastfeeding women, as well as those showing signs of clinical inflammation or viral, bacterial and fungal infections (including herpes), should avoid Desirial. Additionally, those with hypersensitivity to hyaluronic acid should not be treated with this filler.

It should be noted that all patients should attend a consultation with a physician before undergoing treatment with Desirial.


Desirial side effects


Post-injection reactions may occur after treatments with Desirial. These are generally minor, and often clear up within 1 week; if they persist beyond this, physician intervention is necessary.


Common side effects:


  • Itching
  • Sensitivity at the injection site
  • Minor pain
  • Bruising


Possible adverse effects:


  • Allergy
  • Hypersensitivity
  • Discolouration of the injection site
  • Transient erythema


What is it made of?


Desirial is a hyaluronic acid-based filler. This lubricating fluid is found naturally in the body’s joints, skin, tissues, and eye sockets, where it helps to retain collagen levels, maintain elasticity, and increase moisture levels. Now, it is used in a wide variety of products, including supplements, face serums, and injectable fillers, to increase skin’s youthful glow.

What’s more, Desirial contains the antioxidant mannitol, which is used to help the gel maintain its structure and strength, reduce swelling, and soothe any redness caused by injection. Mannitol is naturally present in celery, olives, and raspberries, and is commonly produced via the hydrogenation of fructose. This sugar alcohol has a variety of medical applications, including the relief of certain symptoms of glaucoma, the lowering of increased intracranial pressure, and the sweetening of diabetic foods.

Ingredients: IPN-like cross-linked sodium hyaluronate 19 mg/ml.
Size: 2 x 1ml pre-filled syringe.
Manufacturer: Vivacy.
Origin: Europe.
Also Included: Contains 2 x 27G 1/2" needles and 2 x 30G 1/2" needles, packaging insert.
Storage: Store between 2° - 25° C.
Remarks: Sterile packaging.