DYSPORT® 500u (Romanian)

DYSPORT® 500u is a botulinum toxin type A product used for both therapeutic and aesthetic indications. It works by blocking nerve signals to targeted muscles, reducing excessive contractions and smoothing wrinkles. It is commonly used to treat cervical dystonia, upper limb spasticity, and glabellar lines. The product is supplied in a freeze-dried powder form and must be reconstituted before use. DYSPORT® is not interchangeable with other botulinum toxin products due to differences in potency and formulation.

Key Features

• Highly effective in treating neuromuscular disorders and aesthetic concerns.
• Long-lasting effects, with results typically visible within days and lasting several months.
• Multiple indications, including cervical dystonia, upper limb spasticity, and glabellar lines.

DYSPORT® 500u is supplied in a single-use sterile glass vial containing 500 units of abobotulinumtoxinA. The packaging includes a unique hologram for verification, ensuring authenticity and safety.

Ingredients

• Active Ingredient: AbobotulinumtoxinA (500 Units per vial).
• Excipients: Human albumin and lactose.
• Dilution: Requires preservative-free 0.9% Sodium Chloride Injection for reconstitution.

DYSPORT® 500u is approved for several indications, addressing both medical and aesthetic needs.

Therapeutic Indications

• Cervical Dystonia: Reduces muscle contractions in the neck.
• Upper Limb Spasticity: Helps decrease increased muscle tone in the elbow, wrist, and fingers.
• Lower Limb Spasticity in Pediatric Patients: Approved for use in children aged 2 years and older.

Aesthetic Indications

• Glabellar Lines: Temporarily smooths moderate-to-severe frown lines between the eyebrows in adults under 65 years of age.

Contraindications

• Hypersensitivity to botulinum toxin or excipients.
• Infection at the proposed injection site.
• Allergy to cow’s milk protein.

Side Effects

• Common: Injection site pain, headache, muscle weakness.
• Serious: Difficulty swallowing, breathing issues, blurred vision.

Rare but severe: Distant spread of toxin leading to respiratory complications.

DYSPORT® 500u is administered via intramuscular injection, with dosage varying by indication. Proper dilution and storage are essential for safety and efficacy.

Administration Technique

• Cervical Dystonia: Initial dose 500 Units divided among affected muscles.
• Glabellar Lines: 50 Units total, injected into five sites (10 Units each).
• Upper Limb Spasticity: Dose based on severity and muscle involvement, 250-1000 Units per session.
• Pediatric Lower Limb Spasticity: 10-15 Units/kg per limb, not exceeding 30 Units/kg or 1000 Units total.
• Reconstitution: Mix with preservative-free 0.9% Sodium Chloride Injection, following specific dilution guidelines.

Storage

• Store at 2°C to 8°C (36°F to 46°F) in the original container.
• Do not freeze reconstituted product.
• Use within 24 hours after reconstitution.
• Protect from light and contamination.
• Dispose of expired vials or unused product as medical waste.

DYSPORT® 500u provides a clinically proven solution for neuromuscular and aesthetic treatments, ensuring long-lasting results when used correctly.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.