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Industrie Biomediche
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Plasmolifting Centrifuge XC 2000


Plasmolifting is a non-invasive and non-toxic medical procedure that involves injecting areas displaying various signs of aging with an autologous platelet-rich plasma (PRP)-based implant known as Plasmogel. This PRP is derived from patient’s own blood using the Plasmolifting Centrifuge XC 2000, a centrifuge machine that separates PRP from red and white blood cells using centrifugal force that is created from rotation of constant speed (4000 rpm) for five minutes. This tube holder for this device comes in two sizes which are six 10ml tubes and six 15ml tubes. All components of Plasmolifting are manufactured by an Italian company, Industrie Biomediche & Farmaceutiche. 


What is it used for?

Plasmolifting Centrifuge XC 2000 is designed to be used during a Plasmolifting treatment session to separate the PRP from the rest of the blood using centrifugal force. The extracted PRP is then processed with heat to form the biocompatible and biodegradable Plasmogel that can be used to correct the following aesthetics flaws:


  • Skin inelasticity associated with weakening of dermal framework
  • Acne scarring
  • Lines and wrinkles (e.g. marionette lines, nasogenian furrows)
  • Unsculpted facial contours (e.g. jawline, cheekbones, chin)
  • Loss of facial volume 


How does it work?

Plasmolifting is a non-toxic and non-surgical medical treatment that is designed to regenerate healthy tissues via administration of autologous platelet (APT) injections made from patient’s own blood. Platelets is one of the components of blood. Other components include the white blood cells and red blood cells. Platelets are important for the normal blood clotting mechanism. Extensive research done on the biological properties and functions of platelets demonstrated their ability to produce potent growth factors that can repair and regenerate tissues. While autologous PRP injection is a firm fixture in regenerative medicine encompassing various medical fields (e.g. orthopedics, sports medicine, urology), it is also widely used in aesthetic dermatology as it can successfully correct dermal aging signs like wrinkles and volume loss. Plasmolifting therapy involves centrifuging and incubating patient’s blood to form an injectable PRP-based implant known as Plasmogel. This medical device is unlike other blood centrifuging systems on the market as it is able to extract 20% more PRP from blood. 


How to use it?

Plasmolifting therapy should be attempted aseptically. Besides that, it is very important that you only perform this medical treatment on patients who are free from any contraindicating conditions. Start the procedure by preparing the patient for blood sampling and draw 9cc of blood from the patient. Ensure that this blood is safely drawn into the Plasmolifting PRP Gel tube via a vacutainer. Invert the glass tube filled with patient’s blood sample about five to six times to recover the leuco-platelet layer deposited under the anticoagulant separating gel. Next, place the blood-filled tube in the Plasmolifting Centrifuge XC 2000 device and insert an even number of tubes filled with the same volume of the drawn blood on the opposite end of the device to ensure smooth rotation. If the tube is too short for the tube holder, place some soft foam to ensure that the tube is snug in the holder. Adjust the time and speed of rotation manually by pressing on the “switch” button. For best results, perform the centrifugation at 4000rpm for five minutes. The device has a memory setting that enables the previous program to run for your convenience. Following the completion of the centrifugation process, extract the PRP using a sterile syringe and incubate it at 95°C for three to six minutes until the Plasmogel is formed. You may then administer the Plasmogel into areas showing signs of aging via intradermal or supraperiosteal injections. Discard all used medical supplies at the end of the session. 


How long does it last?

The injected Plasmogel can last for about three months following intradermal or supraperiosteal administration before it is metabolized into the surrounding tissues. The treated areas should remain plump, smooth, and rejuvenated for at least two years before the existing aging signs start appearing again. That being said, the actual residence time of the Plasmogel and the duration of skin improvements vary based on patient’s age, lifestyle habits, health status, and skin condition. 


Is it safe?

Yes, Plasmolifting Centrifuge XC 2000 is a very safe centrifuge device that should be handled by a licensed practitioner who is experienced in centrifuging blood samples. The device must be supplied with a voltage of 220v/50hz for it to work efficiently. It is also designed to stop automatically if the lid is open. If the device becomes faulty, it is important that you send it back to the manufacturer or authorized service provider instead of attempting to fix it by yourself.  Patients can be safely injected with autologous Plasmogel as it poses a very low risk of allergic and rejection reactions. That being said, the following patients must not be treated using this medical device due to poor safety profile:


  • Patients who are allergic to anticoagulants (e.g. heparin)
  • Patients with certain medical conditions (e.g. acute infectious, systemic blood diseases, malignant tumors, mental illness)


It is extremely important that you read the package insert carefully and advise your patients about the contraindications, warnings, and precautions. 


What are the side effects?

While the centrifuge machine itself is generally harmless if handled correctly, the process of injecting Plasmogel into the skin may result in the following injection site reactions:


Common side effects

  • Swelling
  • Tenderness or pain
  • Bruising
  • Itchiness
  • Redness


The inflammatory reactions above are generally very mild and should subside spontaneously once the skin recovers. However, patients are also at risk of developing other more serious adverse secondary aftereffects such as:


  • Pustules
  • Infections
  • Allergic reactions


Always read the package insert carefully for a more detailed description of all possible side effects. Educating your patients about these side effects and the appropriate aftercare methods are absolutely important and must be done during the pre-procedural consultation session.    


What is it made of?

Plasmolifting is an innovative medical treatment that induces restoration and regeneration of damaged and old tissues. In the field of aesthetic dermatology, Plasmolifting is used to improve the appearance of skin displaying signs of aging such as discoloration, inelasticity, wrinkles, undefined facial contours, and loss of skin volume. PRP is extracted from the patient’s own blood via centrifugation before it is heat-processed to form Plasmogel which is then administered via intradermal or supraperiosteal injections. Plasmolifting Centrifuge XC 2000 is a centrifuge machine that is designed to separate the PRP from other blood components using rotation of constant speed (4000rpm) for five minutes. This machine is designed to balance out the tubes’ weight during centrifugation process. The tube holder comes in two sizes which are six 10ml tubes and six 15ml tubes.