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PLURYAL® MESO II  3-5ml vials


MD Skin Solutions
Active Substance(s):
Sodium hyaluronate
Pack Size:
3-5ml vials
Package insert, 6 traceability labels

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What is Pluryal Meso 2?


Pluryal Meso 2 is a biorevitalisation treatment used to rejuvenate skin via a non-invasive mesotherapy procedure. This transparent, injectable skin-boosting solution is packed with hyaluronic acid fragments and an amino acid complex with choline. It is supplied in 5mL ready-to-use ampoules. A box of Pluryal Meso 2 comes with 3 preloaded ampoules, 2 traceability labels for each ampoule, as well as product information leaflet. Store this sterilised and fragile item in its original packaging in a clean room at a temperature between 2 and 25. Avoid heat, frost, and light. This is a European product created by MD Skin Solutions.


What are the ingredients?


Active Ingredients:


  1. Hyaluronic acid sodium salt
  2. Choline bitartrate
  3. Amino acid complex
  • glycine
  • L-serine
  • L-alanine
  • L-proline
  • L-lysine hydrochloride
  • L-cysteine


Other Ingredients: Sodium chloride, phosphate buffer system, water


What is it used for?


Pluryal Meso 2 is an injectable biorevitalisation solution used in mesotherapy to invigorate patients whose skin is affected by early signs of ageing, such as fine lines. The areas that respond well to this treatment are the face, neck, decolletage and the back of hands. After treatment, these areas appear smoother and brighter.


How does this dermal filler work?


Early signs of ageing are marked by appearance of fine lines and spots on skin. Some patients may also complain of dull, dry and saggy skin. All this happens when normal cell regeneration and function slows down due to biological maturing. In addition, outside influences, like excessive sun damage and smoking, introduce free radicals to the body. Free radicals are highly reactive particles that cause damage once they come into contact with skin cells. As a result, skin becomes more problematic and worn out.

Mesotherapy is a non-surgical procedure that works by injecting skin-rejuvenating ingredients (e.g. hyaluronic acid, multivitamins, natural plant extracts, enzymes) into the dermal layer of the skin. The biosynthetic ability of manufacturing collagen is improved, allowing more collagen as well as elastin to be created. Pluryal Meso 2 consists of hyaluronic acid, choline and an amino acid complex, which provides hydration to the skin. After therapy, dermal issues like fine lines, dullness, spots, and sagging skin are erased and skin appears radiant.


How to inject it


As with any other injectable, check that the skin revitalisation solution is still within its shelf life and the sterile packaging is intact. Clean and sanitise the proposed injection sites carefully. Inject Pluryal Meso 2 intradermally into the surface layer of the dermis via a series of micro-injections. Once all the areas have been corrected as desired, discard any leftover solution and used medical supplies. A single procedure typically takes about half an hour to complete with desirable results appearing almost instantly afterwards. Patients receiving Pluryal Meso 2 therapy are recommended to get a treatment every 30 days.

Only accredited medical practitioners with expertise in mesotherapy can purchase and administer this biorevitalisation solution. Ensure that aseptic techniques are used during the entire treatment session. During initial consultation, analyse the patient’s medical record to ensure suitability and advise them to stop taking aspirin and/or vitamin C a week before the scheduled treatment session. Combining this biorevitalisation solution simultaneously with other dermal procedures (e.g. dermabrasion, deep chemical peels) is not recommended. Refer to the product information leaflet for more information on usage instructions.


How long does this filler last?


Skin is rejuvenated almost immediately following the first treatment session and the improvements become more obvious over time. This is why weekly intensive treatment sessions are recommended for patients who have just started Pluryal Meso 2 therapy. Administer 1 treatment every 30 days.


Is this product safe?


Yes, Pluryal Meso 2 therapy is safe and has undergone clinical studies to ensure compliance with the European Commission (CE). The injectable solution has been approved by international regulatory agents. That being said, this mesotherapy solution is contraindicated in certain cases:


  • Those with hypersensitivity to hyaluronic acid;
  • Those with a tendency to develop raised scars;
  • Those with autoimmune disorders;
  • Those with a history of streptococcal infections;
  • Those on immunomodulatory agents;
  • Those with active dermal problems (e.g. acne, herpes) on proposed treatment areas.


Also, patients who are pregnant or breastfeeding or below 18 years of age should not receive Pluryal Meso 2 injections. Refer to the product information leaflet for more information on contraindications, precautions and warnings.


Pluryal Meso 2 side effects


Usually patients respond extremely well to Pluryal Meso 2 injections. However, some clients might develop post-treatment inflammatory reactions.


Common side effects:


  • Pain
  • Redness
  • Rash
  • Itching
  • Swelling


Patients generally recover from these side effects within a week. Patients may also experience more rare effects.


Rare adverse reactions:


  • Tissue death
  • Formation of inflamed lumps
  • Hypersensitivity


Patients should be encouraged to obtain quick medical treatment if any the symptoms worsen or last for longer than a week. Refer to the product information leaflet for more information on side effects.


What is it made of?


Pluryal Meso 2 is a biorevitalisation solution used to rejuvenate skin via a non-invasive mesotherapy procedure. It is made of hyaluronic acid sodium salt, choline bitartrate, amino acid complex, sodium chloride, phosphate buffer system, and water. All the ingredients are of non-animal origin.

Ingredients: Hyaluronic acid sodium salt, Choline bitartrate, Glycine, L-serine, L-alanine, L-proline, L-lysine hydrochloride, L-cysteine, sodium chloride, phosphate buffer system, water.
Size: 3 x 5ml vials.
Manufacturer: MD Skin Solutions.
Origin: Europe.
Also Included: For each vial, the box contains two traceability labels , packaging insert.
Storage: Store between 2℃ and 25℃.
Remarks: Sterile packaging.