DYSPORT® 500u (English/Korean)

DYSPORT® 500u is a botulinum toxin type A product used for both therapeutic and aesthetic applications. It functions as a neuromuscular blocking agent, inhibiting acetylcholine release at nerve terminals, which leads to muscle relaxation. Approved by the FDA, it is indicated for the treatment of cervical dystonia, upper limb spasticity, lower limb spasticity in pediatric patients, and glabellar lines. The effects are temporary, requiring periodic reinjections. DYSPORT® has a different unit measurement compared to other botulinum toxins, and doses are not interchangeable with Botox or other brands.

Key Features:

• FDA-approved for therapeutic and cosmetic applications, including cervical dystonia and facial lines
• Contains abobotulinumtoxinA, a potent neurotoxin that reduces muscle activity
• Different unit potency than Botox, requiring specific dosing calculations​

DYSPORT® 500u is supplied as a freeze-dried powder in a single-use glass vial. Each vial contains 500 units of abobotulinumtoxinA, designed for intramuscular injection. The vial comes in a box containing either one or two vials, with a unique hologram for authenticity verification.

Ingredients:

• Active Ingredient: AbobotulinumtoxinA (botulinum toxin type A)
• Inactive Ingredients: Human albumin and lactose
• Contains traces of cow’s milk protein (patients with allergies to cow’s milk should avoid use)​

DYSPORT® is indicated for multiple conditions affecting muscle control:

Therapeutic Indications:

• Cervical dystonia: Reduces excessive neck muscle contractions
• Upper limb spasticity: For adult patients with involuntary muscle stiffness
• Lower limb spasticity in pediatric patients (ages 2+) due to cerebral palsy

Aesthetic Indication:

• Glabellar lines: Reduces moderate to severe frown lines in adults under 65

Contraindications:

• Hypersensitivity to botulinum toxin or its components
• Infection at the injection site
• Patients allergic to cow’s milk protein​

Side Effects:

• Common: Muscle weakness, dry mouth, fatigue, pain at injection site
• Severe: Difficulty breathing/swallowing, blurred vision, urinary incontinence
• Risk of toxin spread: Symptoms may appear hours to weeks after injection, including difficulty swallowing, respiratory distress, or paralysis​

DYSPORT® is a lyophilized (freeze-dried) powder, requiring reconstitution with preservative-free 0.9% Sodium Chloride Injection before use.

Administration Technique:

• Intramuscular injection only
• Dilution guidelines:
  • 500-unit vial:
    • 1 mL diluent = 50 Units per 0.1 mL
    • 2.5 mL diluent = 20 Units per 0.1 mL
    • 5 mL diluent = 10 Units per 0.1 mL
• Re-treatment: Should occur no sooner than every 12 weeks​

Storage Recommendations:

• Store at 2°C to 8°C (36°F to 46°F)
• Do not freeze after reconstitution
• Protect from light
• Use within 24 hours after dilution​

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.