DYSPORT® 500u (Czech)

DYSPORT® 500u is a botulinum toxin type A product used for both therapeutic and aesthetic purposes. It works as a neuromuscular blocking agent, temporarily relaxing targeted muscles to treat conditions such as cervical dystonia, limb spasticity, and glabellar lines. DYSPORT® 500u is formulated for intramuscular injection and must be administered by a trained healthcare professional. Its effects are temporary, with treatment sessions typically required every 12-16 weeks for therapeutic applications.

Key Features:

• Versatile Applications: Treats cervical dystonia, upper limb spasticity, pediatric lower limb spasticity, and moderate-to-severe glabellar lines.
• Proven Efficacy: Clinical studies confirm effectiveness, with results lasting 12-16 weeks, depending on the condition.
• Precision Dosage: Available in a 500-unit vial, allowing for controlled reconstitution and administration.

DYSPORT® 500u is supplied as a single-use vial containing a lyophilized powder for reconstitution. The vial is packaged in a protective carton with a unique hologram for authenticity verification.

Ingredients:

• Active ingredient: AbobotulinumtoxinA – 500 units per vial.
• Inactive ingredients:
  • Human albumin (0.125 mg per vial)
  • Lactose (2.5 mg per vial)

DYSPORT® 500u is indicated for multiple medical and aesthetic uses. It is prescribed for:

• Cervical dystonia: Reducing neck muscle spasms in adults.
• Upper limb spasticity: Treatment for increased muscle tone in elbow, wrist, and finger flexors in adults.
• Lower limb spasticity in pediatric patients: For children aged 2 years and older.
• Glabellar lines: Temporary reduction of moderate-to-severe frown lines in adults under 65 years old.

Contraindications:

• Hypersensitivity to botulinum toxin or formulation components.
• Active infection at the proposed injection site.
• Neuromuscular disorders (e.g., myasthenia gravis).

Side Effects:

Common side effects include:

• Injection site reactions: Pain, redness, swelling.
• Muscle weakness: Temporary reduction in muscle strength.
• Dysphagia (difficulty swallowing): Particularly in cervical dystonia patients.
• Flu-like symptoms: Fever, fatigue, and headache.

Rare but severe effects include distant spread of toxin, leading to breathing difficulties and dysphagia.

DYSPORT® 500u is administered via intramuscular injection. The dosage and injection sites vary depending on the condition being treated.

Administration Guidelines:

• Cervical dystonia: 500 units, divided among affected muscles, with re-treatment every 12-16 weeks.
• Glabellar lines: 50 units divided into five equal 10-unit injections.
• Upper limb spasticity: Dosing varies based on muscle size and severity, typically 500-1000 units per session.
• Pediatric lower limb spasticity: 10-15 units/kg per leg, adjusted based on response.

Storage Instructions:

• Store unopened vials at 2-8°C (36-46°F).
• Protect from light and do not freeze after reconstitution.
• Use reconstituted solution within 24 hours.

Dispose of expired vials according to medical waste protocols.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.