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RADIESSE® 0.8ml 30% 1-0.8ml prefilled syringe


Merz Pharma
Active Substance(s):
Calcium hydroxylapatite
Pack Size:
1-0.8ml prefilled syringe
Package insert

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What is Radiesse?


Radiesse is an innovative dermal filler that provides non-surgical face lifting with natural and long-lasting results. It can be used both for facial folds and wrinkles or in the back of the hands to replenish lost volume. The operating principle of this wrinkle treatment differs from other skin fillers since it provides many benefits long after volumizer has already been injected. It continues to stimulate body’s natural collagen so the desired fresh, natural look is the result.

In comparison with regular wrinkle fillers which are comprised of HA (hyaluronic acid), it provides correction for 12 months or even longer. The effects of this volumizer have been well-studied and it has been used in the U.S. for more than 20 years. It is safe and does not cause any inflammatory reaction or migration after injection; in addition, it boasts of minor side effects. Nowadays this skin filler is praised as a quintessence effectiveness, safety and incredible results.


What is it used for?


Injectable skin fillers can provide a more youthful and fresh look; moreover, it doesn’t cost a fortune in comparison with traditional facelifts. Radiesse is an innovative wrinkle treatment that fills lines and hollows in less than a half an hour with the lost-lasting natural results. Long-lasting result is another privilege of this skin filler: the volumizer’s effect lasts up to 15 months. The one is used for smoothing nasolabial folds, corner of nose and mouth, for correcting volume loss and for moderation of severe facial folds.


How does it work?


To look younger and beautiful, it is not enough just to get rid of folds and wrinkles. The secret of youth is hidden in facial volumes that are being lost year by year and as a result, one has natural collagen destruction. Radiesse is a skin filler comprised of Calcium Hydroxylapatite or CaHa; it could be described as microspheres suspended in a special gel carrier.

Once volumizer has been injected, it works to add an immediate volume and desired correction. After injection, the gel is being absorbed and body simply metabolizes CaHa microspheres so only natural collagen is left in the body.


How to inject?


When it comes to volumizer injection, Radiesse is full of advantages. First, the injection is almost painless. Second, this wrinkle filler does not leave any pronounced serious edema and allows patient to be back to his normal life in a day or so.

Smile lines, corners of the mouth, marionette lines, pre-jowl fold are just a few sites where this filler could be injected. The volumizer is being injected through a thin, small needle placed under the skin in a few seconds.


How long does it last?

One of the biggest advantages of Radiesse is instant result. One can see them right upon injection: the filler restores flat skin adding volume to smooth out signs of aging. Another advantage of this treatment is that fully natural-looking, safe and great results may last up to 13-15 months or even more. Thus, the volumizer could be injected just once a year or even every 15 months; such procedures frequency saves time and money.

Is it safe?


Radiesse has managed to gain popularity not only in the US but all over the world due to its safety and excellent results that overcome patients’ expectations. It was well-studied and now this wrinkle filler has more than 20 years of use in medicine and cosmetology. The drug has the U.S. and Food and Drug Administration (FDA) approval for facial augmentation. However, there are no medical device or filler which is entirely risk-free.

The testing of Radiesse has proved that people who have an allergy to its components or had several allergies in the past, have bleeding disorders and pregnant or breastfeeding women are strictly forbidden to use this filler.


Radiesse Side effects


Taking into account all abovementioned advantages of this soft-tissue filler, Radiesse could be considered as safe and effective volumizer. Numerous researches prove that if used properly, CaHa which is the main component of this facial filler, is well-tolerated.

The majority of desirable properties can be easily reached with this drug. However, it is no secret a wrinkle filler without side effects has not been invented yet. Never-the-less, this volumizer shows low rate of side effects.

Common side effects


When it comes to frequent adverse events, they are:

  • Bruising
  • Pain
  • Itching

Usually these side effects are mild and last up to 2-12 hours; the full rehabilitation usually takes no more than 48 hours. There are other side effects which may follow injection, you must ask your doctor or health care consultant about any side effects if they don’t go away in 12+ hours after injection.


Severe side effects


According to FDA, dermal fillers can cause severe side effects, however, the percentage of them is extremely low: between 0.9 and 2 %. When it comes to Radiesse the following severe side effects are possible:

  • Ecchymosis
  • Erythema
  • Needle jamming
  • Nodule
  • Pruritus

In case you feel any of these effects after injection, contact your doctor immediately. Remember that you must tell your doctor about all supplements and drugs you use even before the injection.

What is it made of?


Radiesse is made of micro calcium spheres hidden in an aqueous gel carrier. The ingredients of these small spheres are similar to minerals in human’s body, that’s why no allergy test is required. As time and aging goes, cells absorb both water-based gel and microspheres, leaving only natural collagen in the body. Speaking about wrinkle treatment active substance, it is Calcium Hydroxylapatite which stimulates body to produce new collagen at injection sites.



Name:RADIESSE™ Moderate Fill 0.8 cc
Ingredients:Synthetic calcium hydroxylapatite suspended in a gel carrier (particle size range of 25-45 microns).
Size1x0.8mL pre-filled syringe.
Also Included:Package insert. Two sterile 28G T.W.3/4” needles. A set of tractability labels.
Storage:Store between 15 – 32℃.
Remarks:Sterile packaging.