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WHAT IS YVOIRE?

Yvoire is a range of innovative injectable dermal fillers made of cross-linked hyaluronic acid. These fillers are able to instantly correct a wide variety of skin depressions and maintain results for an extended period of time. There are 2 fillers in this range and both of them share the same hyaluronic acid potency. However, these 2 products are used for different purposes and come with their own unique packaging:

• Yvoire Classic S is made of 22mg/mL of cross-linked hyaluronic acid gel supplied in a 1mL syringe. Each box of this filler is sold with 1 prefilled syringe and comes with 27G and 30G thin-walled sterile needles, and a device information leaflet.
• Yvoire Contour is made of 22mg/mL of cross-linked hyaluronic acid gel supplied in a 1mL syringe. A box of this filler is sold with 1 prefilled syringe and with 27G and 30G thin-walled sterile needle, and a device information leaflet.

These fillers come in sterile packaging and have a shelf-life of 24 months. They must be stored away from light in an airtight container in a temperature ranging from 2°C to 25°C. The formulation of these soft tissue hyaluronic acid fillers was developed and perfected by LG Life Sciences.

WHAT IS IT USED FOR?

Some of the major signs of ageing in the skin are loss of elasticity and wrinkle formation. Yvoire was created to combat these signs instantly.

• Yvoire Classic S has been formulated with hyaluronic acid particles with an average size of 400um. This makes it is ideal for correcting moderate wrinkles, as well as for hydrating parched areas. It can also be injected into the lips for a beautifully sculpted pair of lips.
• Yvoire Contour has been formulated with a combination of fine and large hyaluronic acid particles. The gel possesses high cohesiveness and is perfect for treating severe wrinkles, as well as for volumising sunken areas caused by lipoatrophy. Even facial contours can be easily defined using this temporary implant.

HOW DOES THIS DERMAL FILLER WORK?

Skin gets its distinctive strength and elasticity from collagen and elastin fibres. These structural proteins form a pliable yet strong scaffolding for other functional cells to cling onto. Hyaluronic acid also plays a part in maintaining the integrity of skin structure as it deeply hydrates those fibres and helps prevent disintegration. In its younger years, the skin works very efficiently and appears smooth and elastic. However, as ageing takes a toll on skin structure and functions, genetic signalling slows down production of these skin cells, and maintenance processes like the shedding of dead cells become irregular. As a result, the skin loses its elasticity and radiance, leading to wrinkle formation on regions where habitual expressions take place.
Fine lines and wrinkles exacerbate into more pronounced facial creases when external factors like excessive sunlight exposure, smoking, and pollution harm the already weakened skin. These external aggressors introduce free radicals, which further injure the skin cells and interfere with normal processes. Yvoire has been formulated with synthetic hyaluronic acid to combat these skin issues. Cross-linked hyaluronic acid gel helps to instantly volumise and lift collapsed areas of the skin. The gel is also processed to contain highly viscoelastic and cohesive hyaluronic acid particles, which allows for a smooth injection process and provides natural-looking results. With adequate correction, the skin reverts back to its smooth and supple appearance.

HOW TO INJECT IT?

The initial consultation session is the time to discuss your patient’s treatment goals. A complete review of their medical history (e.g. existing medical conditions, supplements and drugs taken), as well as a facial assessment is vital in determining the appropriate procedural plan. This is also the time to prepare them for the procedure by discussing the precautions, warnings, and probable effects of the treatment. Once they are deemed ready, set a date for their treatment session.
Dermal filler injections must always be performed in accordance with aseptic guidelines, so you must start by sanitising the proposed treatment sites with a suitable disinfectant. Assemble the medical device by securing a sterile needle onto the Luer lock of the preloaded syringe.
Once both the treatment areas and device are ready, you may inject the dermal filler slowly via an appropriate administration method based on the area of treatment. Some good injection techniques are serial puncture or linear threading.
After correction is complete, massage the treated areas gently and discard any remaining filler gel as well as all used needles.
Refer to the device information leaflet for more detailed instructions.

HOW LONG DOES IT LAST?

Due to their cross-linking technology, these fillers are able to provide hydrating and volumising effects for approximately 6 months, with some patients seeing results for up to a year.

IS THIS PRODUCTS SAFE?

Yes, Yvoire implants are well-known for their safety and quality. The hyaluronic acid molecules used in these products are extracted from a tightly-regulated process of biofermentation. Extracted particles are purified and cross-linked into highly cohesive, transparent, and colourless gel. Since the gel is synthetic, the risk of disease-transmission and hypersensitive reactions are greatly reduced. Despite its superior safety and quality, these fillers are still contraindicated in the following patients:

1. Patients who are allergic to hyaluronic acid-based products;
2. Patients who have a history of allergic attacks;
3. Patients who have a history of streptococcal diseases;
4. Patients who are predisposed to developing hypertrophic scarring;
5. Patients who have bleeding diseases;
6. Patients who have skin disorders (e.g. acne, hives, herpes breakouts) on targeted treatment areas;
7. Patients who are still recovering from previous dermal treatment (e.g. dermabrasion, chemical peels);
8. Patients who are pregnant or breastfeeding;
9. Children.

Refer to the device information leaflet for more contraindications.

YVOIRE SIDE EFFECTS

Patients may experience localised inflammatory responses caused by the injection process.

COMMON SIDE EFFECTS:

• Redness;
• Stinging sensation or pain;
• Swelling;
• Slight fever.

These post-injection responses usually appear immediately following injections, though their appearance could be delayed. Nevertheless, the reactions typically last only for a week and will resolve on their own.

SERIOUS SIDE EFFECTS:

• Abscess (pus buildup);
• Hypersensitivity.

These reactions are severe and require immediate treatment at the nearest hospital. Refer to the device information leaflet for more side effects.

WHAT IS IT MADE OF?

Yvoire is a family of injectable dermal fillers made of cross-linked hyaluronic acid. There are 2 fillers in this range and both of them share the same cross-linked, non-animal hyaluronic acid with a potency of 22mg/mL. Each product is able to instantly correct a wide variety of skin depressions and maintain these results for an extended period of time.