Syringe with vial.
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Last Updated On: April 24, 2024

Restylane Reimagined: Creative Applications for Non-Facial Areas

Published on: Apr 12, 2024

According to statistics from the American Society of Plastic Surgeons, doctors performed an estimated 15.9 million minimally invasive cosmetic procedures in 2018, marking a 2% increase from 2017 and a significant 228% increase from 2000. These procedures encompass both facial and non-facial regions of the body.

In recent years, the versatility of Restylane has expanded to non-facial regions such as the hands, neck, knees, and buttocks, providing patients with a comprehensive approach to aesthetic enhancement. This evolution signifies a paradigm shift in cosmetic medicine, as the focus has broadened beyond facial features to include the entire body’s appearance and texture.

This article delves into Restylane’s advancements in rejuvenating non-facial areas, highlighting its transformative impact on aesthetic enhancement beyond traditional facial treatments.

Key Takeaways

  • Restylane offers a versatile solution for non-facial rejuvenation, addressing concerns like hands, neck, knees, and buttocks. This treatment improves skin texture, hydration, and volume, providing natural-looking results that last up to a year.
  • Patient assessment and treatment planning are crucial for successful non-facial Restylane injections. Healthcare providers should consider each patient’s unique anatomy and expectations to tailor the treatment, ensuring optimal outcomes and patient satisfaction.
  • Despite initial concerns, studies and real-life examples confirm the safety and effectiveness of using Restylane in non-facial areas. Patients can confidently explore these innovative treatment options, empowered by informed decision-making and guided by skilled healthcare providers.

Understanding Restylane and Its Versatility

Restylane is a game-changer in cosmetic enhancements. It is the first HA dermal filler approved by the US FDA. This clear gel from hyaluronic acid restores volume to aging skin and smooths out wrinkles and lines without animal-based ingredients. Restylane restores a more youthful appearance without requiring surgery by raising scar depressions and enhancing features that have flattened over time.

Restylane, designed to replicate the body’s natural hyaluronic acid, effectively rejuvenates areas such as the lips and smile lines by providing structural support. This unique characteristic addresses common signs of aging like dryness, loss of fullness, and reduced elasticity and offers versatility in volumizing different facial regions, including saggy earlobes and thin skin. 

Non-Facial Areas for Restylane Applications

Restylane syringe injection
  • Restylane for Hand Rejuvenation: Restylane Lyft is ready to reveal younger-looking hands. It’s a real game-changer, being the first dermal filler that got a thumbs up from the FDA specifically for hand rejuvenation.
  • Restylane for Neck and DĆ©colletage Enhancement: Restylane injections bring new life to the neck and dĆ©colletage area. They add fullness and volume, making skin look younger and smoother. The effect happens because Restylane boosts the body’s hyaluronic acid.
  • Restylane for Knee and Buttock Augmentation: This treatment provides a solution for rejuvenating the knee skin, resulting in a smoother and more youthful appearance. Similarly, it enhances the volume and shape of the buttocks without requiring extensive surgery. Patients increasingly opt for these minimally invasive alternatives due to their rapid results and minimal downtime. 

Considerations and Techniques for Non-Facial Restylane Injections

A doctor explaining Restylane treatment to a patient.

Patient Assessment for Non-facial Areas

Assessing patients for non-facial Restylane treatments requires keen attention to their expectations and the specific area’s characteristics. This step is critical because patient satisfaction hinges on meeting these expectations. Moreover, assessing skin quality and volume loss in areas like the hands, neck, or knees guides how much Restylane the treatment requires.

Treatment planning is equally important because it acts like a roadmap. Doctors use it as a guide to know how much Restylane to use per treatment. Each body part is different, so how we inject into hands differs from knees or necks.

Injection Technique Optimization for Non-facial Rejuvenation

Each patient’s needs are unique, making individual assessment crucial for achieving the best results. Here are some strategies for medical professionals:

  • Choose the Correct Type of Restylane Product: Different products are available, but selecting one that suits the treated area ensures more natural and lasting results.
  • Patient Assessment is Critical: Thoroughly examining the treatment area helps plan the injection strategy for optimal rejuvenation.
  • Customize the Injection Mix: Blending Restylane with anesthetic agents or other diluents can enhance patient comfort and improve outcomes in complex non-facial areas.
  • Use a Cannula When Necessary: For areas needing a softer touch or where bruising is a concern, employing a cannula instead of a needle can be effective, as Restylane’s consistency demands precise application.
  • Pay Attention to Skin Hydration: Beyond adding volume, ensuring that the rejuvenated area maintains improved skin texture and hydration is essential for satisfying aesthetic enhancement.

Benefits of Restylane for Non-Facial Rejuvenation

Restylane harnesses the power of hyaluronic acid to impart a coveted, bouncy texture to the skin. This essential ingredient retains moisture and maintains the skin’s plumpness and elasticity. With Restylane, rough patches and dry spots become smooth. 

Where can Restylane be used? Restylane fillers work beyond the face. Skin gets more hydration and looks smoother, making hands, necks, knees, and even buttocks appear more youthful. These treatments also give lasting results. 

The results of Restylane treatments in non-facial areas can last from six to twelve months. People see differences based on the type of Restylane used. Some might find their treatment lasts closer to six months, while others enjoy benefits for an entire year.

Addressing Concerns and Misconceptions

People often worry about the safety of using Restylane in non-facial areas. But Restylane boasts a remarkable safety profile, primarily due to its compatibility with the body’s natural substances. Adverse reactions are exceedingly rare occurrences.

Misconceptions may lead some to need more time to explore these options. Restylane offers a versatile solution for faces and beyond, backed by positive outcomes and smiles of satisfaction from those who dare to try it.

Case Studies and Testimonials

Restylane isn’t just for the face anymore. Medical professionals have been exploring its uses in other body parts with impressive results. Here’s a quick look at how Restylane is making waves beyond the cheeks and lips:

Before and after of hands.

Image Courtesy of Restylane

  • Hands That Tell a Different Story: A doctor injected Restylane into a patient’s hands, resulting in smoother skin with less visible veins and tendons. The hands looked younger in just one session.
Before and after of neck.

Image Courtesy of Dr. Katie Belaznay

  • Confidence Down to the Neck: Another person was self-conscious about her neckline. After some Restylane shots, those lines started to fade away. She felt more confident wearing necklines that she had avoided for years.
  • DĆ©colletage Delight: It’s not just about looking good in a necklace; it’s about the whole area looking smooth and supple. One patient found her solution with Restylane injections into her dĆ©colletage area, which improved skin hydration and texture.
Before and after of knees.

Image Courtesy of Reflections

  • Knees, Please: Who knew knees could age, too? Well, they do, but Restylane is here to help. A runner struggled with saggy skin around her kneesā€”a few treatments later, she saw a significant improvement, which made her feel better in shorts.
Before and after of buttocks.

Image Courtesy of Skinly Aesthetics

  • Boost for the Buttocks: Not everyone wants or needs surgical enhancements for a fuller backside. Some patients have chosen Restylane as an alternative for subtle buttock augmentation, offering a less invasive option with satisfying results.

Practical Tips and Recommendations

Here are some tips for patients thinking about trying out the treatments:

  • Research Thoroughly Before Deciding: Look into how Restylane works not only on the face but also on other body parts such as hands, neck, knees, and buttocks. 
  • Find a Skilled Provider Experienced in Non-facial Applications: Not all practitioners have ventured beyond the face, so it’s crucial to find one who has.
  • Discuss Your Goals Openly During the Consultation: Whether you want hand rejuvenation or buttock augmentation, being clear about what you need helps craft a plan that suits you.
  • Plan for Downtime After Treatment, Even if Minimal: Swelling or bruising in non-facial areas may show differently than on the face.
  • Care Post-procedure Plays a Significant Role: Avoid touching or massaging treated areas for 6 to 12 hours, and if possible, keep your head elevated while sleeping on the first night.

Recommendations for Healthcare Providers 

Exploring non-facial applications of Restylane opens new doors for improving patient care. This innovative approach caters to a broader range of aesthetic needs and preferences.

  • Get Familiar With the Consensus Recommendations: Understanding what the healthcare industry says about using hyaluronic acid fillers like Restylane for non-facial areas is critical. This knowledge ensures your treatments meet established safety and effectiveness standards.
  • Assess Each Patient Thoroughly: Every person comes with unique concerns and anatomy. A detailed evaluation helps tailor the Restylane application, ensuring optimal results for areas outside the face, such as the hands or neck.
  • Dive Deep Into Product Variations: Not all Restylane products work the same way in every area. Some might be better for adding volume, while others excel at smoothing out wrinkles. Knowing the differences can make a significant impact.
  • Share Knowledge With Patients: Many might need to learn about Restylane’s non-facial uses. Educating them on possibilities and outcomes can guide their decision-making process.
  • Stay Open to Feedback: Listen closely to what patients say after their treatments. Their insights can offer valuable cues on refining techniques or adjusting treatment plans.


Restylane is a clear gel made from hyaluronic acid that can rejuvenate hands, necks, and knees, among other areas. It offers natural-looking results and leaves patients feeling confident with smoother skin. Understanding the benefits and risks is crucial. Innovative options help redefine the standards of aesthetic enhancement and tackle common concerns effectively.


  1. Can Restylane be used on parts of the body other than the face?

Indeed, Restylane can enhance areas beyond the facial region.

  1. What’s a surprising spot to use Restylane that most people don’t think about?

Remarkably, hands can also benefit from a rejuvenating touch with Restylane injections.

  1. Does using Restylane in non-facial areas hurt?

The sensation is akin to a swift jabā€“relatively tolerable.

  1. How long does Restylane last in places like the hands or neck?

Its effects endure considerably, imparting a sleek and youthful appearance.

  1. Is there anything special I need to do after getting Restylane in a non-facial area?

Simply relax and allow the transformation to unfold naturally.

About: Trusted by over 2,000+ global clients since 2014, Maylips has become a leading supplier of cosmetic, skincare, and orthopedic products for medical and aesthetic professionals. Maylips offers a wide range of authentic brand-name products at competitive wholesale prices, sourced from around the world. Whether your practice needs dermal fillers, botulinum toxins, mesotherapy, PRP kits, or other solutions, Maylips can provide high-quality products and exceptional customer service. Maylips is more than just a supplier, it is your partner in achieving your medical and aesthetic goals.


American Society of Plastic Surgeons. (2018). 2018 Plastic surgery statistics report [Report]. Retrieved from

Lee, B. M., Han, D. G., & Choi, W. S. (2015). Rejuvenating Effects of Facial Hydrofilling using Restylane Vital. Archives of plastic surgery, 42(3), 282ā€“287.
Edwards, P. C., & Fantasia, J. E. (2007). Review of long-term adverse effects of using chemically modified animal and nonanimal source hyaluronic acid dermal fillers. Clinical interventions in aging, 2(4), 509ā€“519.