Revolax

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Revolax is a brand of synthetic injectable soft tissue implants that contain non-animal cross-linked hyaluronic acid gel as their active ingredient. The hyaluronic acid molecules are manufactured under a strict laboratory setting and are extracted via biofermentation. Subsequently, they are purified to contain less than 1.2IU/ml of potentially harmful endotoxins. They are then cross-linked with each other using 1,4-butanediol diglycidyl ether (BDDE), a renowned chemical reticulating agent, before they are integrated with fast-acting lidocaine to reduce pain during treatment session. The resulting injectable dermal fillers are biocompatible, biodegradable, viscoelastic, and contain imperceptible levels of bacterial endotoxins and BDDE. Revolax fillers have monophasic and polydensified gel structures that enables them to be injected easily and consistently into the skin. As of now, there are three types of Revolax fillers: Revolax Fine, Revolax Deep, and Revolax Sub-Q; each of these products have corresponding lidocaine-infused versions. Revolax Deep with Lidocaine and Revolax Sub-Q with Lidocaine are made of 24mg/ml of cross-linked hyaluronic acid gel integrated with 0.3% lidocaine, which is a type of rapid-acting anesthetic agent. On the other hand, Revolax Fine, Revolax Deep, and Revolax Sub-Q, and Revolax Fine with Lidocaine are made of 20mg/ml of cross-linked hyaluronic acid. Each Revolax filler is supplied in a sterilized and disposable 1.1ml syringe. Despite their similarities, the soft tissue implants differ in terms of package accessories, injection depth, and indications. Revolax is manufactured by Across, a pharmaceutical company that specializes in making medications, medical devices and equipment, and health foods. The fillers have a shelf life of 24 months, which can be easily maintained if they are stored at a cool and dry place where the temperature is kept between 2℃ to 25℃.

What are they used for?

These fillers are processed to have different viscosities to correct a wide range of aesthetic imperfections. Revolax Fine and Revolax Fine with Lidocaine are designed to instantly remove fine lines, such as perioral lines around the mouth, crow’s feet at the outer corner of the eyes, forehead/worry lines, and neck wrinkles. It is also suitable for smoothening and contouring the lower eyelid regions. Revolax Deep and Revolax Deep with Lidocaine are suitable for correcting deeper wrinkles, such as the nasolabial folds. Since they are also malleable, they can be used to nonsurgically augment the chin, cheeks, and lips. Revolax Sub-Q and Revolax Sub-Q with Lidocaine are able to effectively volumize very deep skin wrinkles and are able to nonsurgically augment the contours of the nose, lips, cheeks, and chin.

Following an injection session with one of these fillers, the treated regions become plumper and free from the filler’s particular indications.

How do they work?

Dermal imperfections like inelasticity and wrinkles form due to unstoppable intrinsic aging of the body. This biological aging is signaled by patient’s genetic makeup. Intrinsic aging acts on the skin by slowing down the rate of cellular turnover, which is the process whereby newer dermal cells replace older dermal cells. This causes the deterioration of skin condition and may make a patient appear haggard or older than their actual chronological age.

How should Revolax fillers be used?

Since injecting a Revolax filler is a minimally invasive aesthetic procedure, stringent aseptic standards should be followed throughout the procedure to reduce the risk of infections or cross-contaminations. Commence the treatment session by assessing your patient’s medical history to ensure that they are completely free from any contraindicating medical conditions. Next, clean and sanitize the proposed treatment region. Assemble the medical device by securing one of needles provided onto the syringe that is prefilled with the particular Revolax filler that is going to be used. The injection technique differs on the basis of the filler used. Revolax Fine and Revolax Fine with Lidocaine should be administered into the superficial dermis. Revolax Deep and Revolax Deep with Lidocaine should be administered into the mid/deep dermis or subcutaneous layer. Revolax Sub-Q and Revolax Sub-Q with Lidocaine should be administered deep into the subcutaneous layer. Once the proposed treatment area has been adequately corrected, discard of any used needles and syringes safely.

How long do these fillers last?

Following an injection session of a Revolax filler, patients should notice immediate improvements to their aesthetic imperfections. These fillers are able to last for about 12 to 18 months. Their long residence time is made possible by the strong cross-links between their hyaluronic acid molecules and their sturdy polydensified gel structure. Implanted Revolax fillers are able to resist premature degradation caused by enzymes and damaging free radicals circulating in the body. That being said, the exact duration of action of any Revolax filler differs on an individual basis. Nevertheless, patients can definitely obtain more filler injections once the initial results wear off.

Are they safe?

Yes, all Revolax fillers are of safe and of high quality. The hyaluronic acid molecules are manufactured biotechnologically under strict laboratory conditions. Most importantly, the fillers are thoroughly purified to contain less than 1.2IU/ml of potentially harmful endotoxins and a negligible level of BDDE. Hence, these European Medical CE-certified fillers pose extremely low risk of immunogenic or rejections reactions in the body. That being said, Revolax fillers are contraindicated in patients that are hypersensitive to hyaluronic acid, hypersensitive to lidocaine or other amide-type anesthetic agents, tend to develop hypertrophic scarring, or have skin infections or inflammations on their proposed treatment region. Patients who are pregnant, breastfeeding, or below the age of 18 are also contraindicated from being treated using Revolax fillers. For a full list of any Revolax filler’s contraindications, refer to its package insert.

What are the side effects?

After an injection of a Revolax filler, patients may experience localized skin reactions on their particular injection site. These reactions can include pain, redness, swelling, and bruising.

The inflammatory reactions above are mild and should subside on their own as the skin recovers. Some patients may also develop other rarer yet serious side effects. Refer to the package insert of a Revolax filler to see a full list of its side effects. Educate your patients on the side effects of the Revolax filler they are going to be injected with so that they can get swift medical attention if the need ever arises.

What are they made of?

Revolax is a brand of completely synthetic, tissue-friendly, and biodegradable soft tissue fillers that are made of cross-linked hyaluronic acid gel. These filler gels are monophasic and have sturdy polydensified structures that enables them to be injected intradermally with uniform extrusion force. Though all Revolax fillers are similar in terms of their hyaluronic acid concentration, they have different degree of complex viscosities and, as a result, can each correct different aesthetic imperfections to bring about plumper and smoother-looking skin. Revolax fillers are a product of Across, a South Korean pharmaceutical company.