What RENEFIL Is Used For
RENEFIL is a hybrid injectable dermal filler designed to temporarily reduce facial wrinkles and restore volume. It combines cross-linked hyaluronic acid (HA) and polynucleotides (PN) to deliver both mechanical filling and skin regeneration effects.

Used to treat facial wrinkles and nasolabial folds through structural support.
Aims to restore facial volume and improve skin texture.
Offers additional skin benefits such as hydration, collagen stimulation, and skin rejuvenation.

What Makes RENEFIL a Good Choice
RENEFIL stands out as the first CE-certified hybrid filler to combine HA, PN, and lidocaine in a single formulation. This unique blend makes it versatile, safe, and long-lasting.

First-of-its-kind HA + PN + Lidocaine combination.
Registered patents in Korea, USA, EU, Russia, Japan, and China.
Proven clinical performance in studies against major competitors.
Engineered for easy injection with low force and smooth flow.
Offers firm volume support and visible skin improvement.

Different RENEFIL Products
Here’s information on the RENEFIL filler product line you can buy on Maylips today:
RENEFIL DEEP PLUS
RENEFIL DEEP PLUS is formulated for correcting moderate to deep wrinkles and restoring facial volume in areas like the nasolabial folds, cheeks, and chin. Its high viscosity and elasticity ensure effective molding and long-lasting support under the skin. With cross-linked hyaluronic acid (20mg/mL) and polynucleotides (1.875mg/mL), this filler offers both structural enhancement and skin-regenerative benefits. The addition of lidocaine (0.3%) improves patient comfort during injection. DEEP PLUS is ideal for practitioners looking to deliver visible volume correction with a smooth injection experience.

Suitable for mid-to-deep dermal layers
Treats volume loss and deeper folds
Combines filling and collagen-stimulating effects
Uses a 27G or 30G needle for precision
Balanced performance for molding and ease of use

RENEFIL LIGHT PLUS
RENEFIL LIGHT PLUS is designed for fine lines, superficial wrinkles, and subtle contouring. It works well on areas like the forehead, lips, and periorbital region, where precision and softness are key. With a smaller particle size (250μm) and smooth texture, it allows for natural-looking refinements without bulk. The hybrid formula—cross-linked HA, PN, and lidocaine—offers hydration, wrinkle smoothing, and patient comfort in one syringe. LIGHT PLUS is well-suited for touch-ups or initial treatment phases in younger patients or delicate facial zones.

Best for superficial wrinkles and delicate areas
Enhances hydration and skin texture
Easy injection with 30G needle
Ideal for first-time filler patients
Minimizes risk of overcorrection or lumping

RENEFIL ULTRA PLUS
RENEFIL ULTRA PLUS is the most robust variant in the lineup, developed for high-volume augmentation and structural reshaping of areas like the chin, jawline, temples, and zygomatic zone. It features the largest particle size (1,000μm) and enhanced rheological properties, giving it high cohesiveness and shape retention under pressure. Despite its density, ULTRA PLUS maintains low injection force, allowing smooth application with consistent results. It’s ideal for patients needing stronger facial definition and longer-lasting volume effects.

Engineered for deep structural support
Maintains shape under skin tension
Uses 27G needle for deep dermal/subcutaneous injection
Excellent molding and lift capacity
Retains volume for up to 12+ months in clinical studies

Best Uses and Target Areas
Each RENEFIL variant is designed to suit different facial zones and aesthetic goals. The product selection depends on wrinkle depth, desired volume, and skin condition.

Fine lines: Forehead, perioral area, lips.
Medium wrinkles: Nasolabial folds, marionette lines, cheeks.
Deep volume restoration: Chin, jawline, temple, zygomatic region.
Effective for both structural filling and skin quality improvement.

Key Ingredients in RENEFIL
RENEFIL combines clinically tested ingredients to ensure efficacy, safety, and performance.

Cross-linked Hyaluronic Acid (20mg/mL): Provides volume and structure.
Sodium Polynucleotide (1.875mg/mL): Enhances skin repair, hydration, and collagen production.
Lidocaine HCl (0.3%): Reduces injection discomfort for patients.
The HA used is EU-origin and EDQM-approved.
Manufactured with minimal BDDE content and extensive purification to reduce risk of reactions.

How It’s Given (Injection Guide for RENEFIL)
RENEFIL is administered as a subdermal injection by a licensed medical professional. The injection technique and depth depend on the selected variant and treatment area.

Packaged in prefilled syringes with 2 sterile needles.
Injected under the skin using appropriate gauge (27G or 30G) depending on the formulation.
Smooth injection experience due to low force requirement and stable viscosity.
No clumping or disturbance during injection, making it predictable and user-friendly.

Storage and Expiry Details
Proper storage ensures the product maintains its safety and efficacy until use.

Store at 2–25°C (36–77°F) in a clean, dry location.
Do not freeze or expose to direct sunlight.
Shelf life is clearly indicated on the packaging.
Single-use only; discard any unused portion after opening.

Possible Side Effects to Know
As with any injectable filler, RENEFIL may cause minor and temporary side effects. These are generally mild and resolve on their own.

Common side effects include redness, swelling, bruising, and tenderness at the injection site.
Low BDDE content and thorough purification reduce risks of adverse reactions.
Clinical trials reported no significant safety concerns over a 6-month evaluation.
Always perform injection under aseptic conditions and by trained professionals to minimize complications.

Where to Buy RENEFIL
RENEFIL is available through licensed medical distributors and aesthetic suppliers. Always ensure the product is sourced from authorized vendors to guarantee authenticity and proper handling.

You can order RENEFIL fillers on Maylips today at wholesale prices!
Quick Answers About RENEFIL
Is RENEFIL safe?
Yes, RENEFIL uses high-quality ingredients and is CE-certified. It has undergone clinical trials and follows ISO 13485 standards.

What makes it different?
It’s a hybrid filler combining HA + PN + Lidocaine, offering both volume and skin regeneration in one product.

How long do results last?
In animal studies, volume retention lasted up to 56 weeks. Most users see effects that persist beyond 6 months.

Who can use RENEFIL?
Licensed medical practitioners can use it on adults seeking wrinkle reduction and facial volume restoration.

What’s the benefit of polynucleotides (PN)?
They stimulate fibroblasts, promote collagen, and support skin healing and hydration, unlike traditional HA-only fillers.