Buy Dermal Fillers

PLINEST® offers a safe, effective way to improve skin texture, elasticity, and hydration using polynucleotides backed by clinical results. Its versatile product range and strong tolerability make it a reliable option for both aesthetic practices and patients seeking natural-looking rejuvenation.

Buy PLINEST® online on Maylips today!

What PLINEST® Is Used For

PLINEST® is an injectable medical device used to revitalize skin, reduce fine lines, and improve skin texture and elasticity. It’s primarily used in aesthetic and dermatological medicine to treat signs of aging and scarring.

• Helps with skin bioregeneration and hydration
• Reduces fine wrinkles, skin laxity, and roughness
• Improves appearance in areas like the face, neck, and décolleté
• Also used in acne scar correction
• Suitable for both preventive care and anti-aging treatment

What Makes PLINEST® a Good Choice

PLINEST® uses PN-HPT™ (Polynucleotides Highly Purified Technology) to trigger natural skin regeneration. It’s safe, well-tolerated, and shown to deliver visible results after just a few sessions.

• Based on deoxyribonucleotide polymers from natural sources
• Over 90% of patients showed visible skin improvement in studies
• Boosts hydration by 14.7% and elasticity by 21.8%
• Minimal side effects and low pain during injection
• Works well alongside other aesthetic treatments like fillers, laser, or microneedling

Different PLINEST® Products

PLINEST® comes in multiple formulas, each tailored to a specific treatment goal. All versions use the same core ingredient, PN-HPT™, but vary in concentration or format to target specific concerns.

PLINEST®

• Standard formulation: PN-HPT™ 40 mg/2 mL
• Packaged in 1 x 2 mL pre-filled syringe
• Includes 2 x 30G ½ needles
• For general skin rejuvenation and wrinkle reduction

PLINEST® EYE

• Specially designed for the periorbital area
• Targets eye contour wrinkles, dark circles, and eyelid sagging
• Lower volume and adapted for delicate skin

PLINEST® HAIR

• Formulated for scalp use
• Supports hair regrowth and scalp revitalization
• Improves scalp hydration and hair follicle condition

PLINEST® ONE

• Single-dose format of 2 mL
• Ideal for clinics preferring single-use applications
• Offers all benefits of standard PLINEST® in a compact version

Best Uses and Target Areas

PLINEST® is versatile and can be used across several areas where skin aging or damage is visible. It’s especially helpful for patients seeking gradual, natural-looking improvement.

• Face: improves tone, firmness, and smoothness
• Neck: reduces laxity and surface lines
• Décolleté: restores hydration and elasticity
• Scars: softens acne scars and improves skin texture
• Eye area: reduces periorbital wrinkles with PLINEST® EYE
• Scalp: supports hair restoration with PLINEST® HAIR

Key Ingredients in PLINEST®

PLINEST® is based on Polynucleotides Highly Purified Technology (PN-HPT™) — deoxyribonucleotide polymers that promote skin regeneration and repair.

• PN-HPT™ 40 mg/2 mL in a sterile, non-pyrogenic gel
• Natural-origin DNA fragments with high biocompatibility
• Triggers cell turnover, tissue repair, and hydration
• Supports skin priming for procedures like peeling, laser, and surgery

The unique PN-HPT™ priming effect makes the skin more receptive to other aesthetic treatments and helps improve overall treatment outcomes.

How It’s Given (Injection Guide for PLINEST®)

PLINEST® is injected intradermally, using either the micro-droplet or linear retrograde technique, depending on the treatment plan. The process should be performed by a trained medical professional.

Protocols:

For General Skin Rejuvenation:

• One session every 14–21 days, total of 3 sessions
• Use 2 mL per session, injected with 30 microdroplets (0.1–0.2 mL each)

For Acne Scars or Advanced Aging:

• 4 mL per session, repeated every 3 weeks, total of 2 sessions

Maintenance:

• Every 1–3 months depending on skin condition and goals

Injection depth should always be intradermal, and the number of treated zones can vary from one to multiple areas during the same session.

Storage and Expiry Details

PLINEST® is stable and easy to store when kept within the recommended conditions.

• Store at room temperature (as indicated on packaging)
• Keep in original packaging until use
• Protect from direct sunlight, moisture, and contamination
• Check expiry date on each unit before use
• Each syringe is single-use only

Proper storage ensures the safety and effectiveness of the polynucleotide gel throughout its shelf life.

Possible Side Effects to Know

PLINEST® is well tolerated by most patients, but minor side effects can occur after injection, as with any intradermal procedure.

Common mild effects:

• Redness, swelling, or tenderness at injection sites
• Bruising or minor discomfort during or after the procedure

Rare risks:

• Small nodules or injection site reactions if improperly placed
• Very low chance of allergic response due to the highly purified nature of PN-HPT™

There were no severe adverse events reported in the product trials, making PLINEST® a safe option when used correctly.

Quick Answers About PLINEST®

How soon will I see results?
Most users notice visible improvements within 30 days after 3–4 sessions.

How long do the results last?
Results can last several months, especially with maintenance treatments every 2–3 months.

Who is a good candidate?
Anyone looking to improve skin texture, elasticity, and tone — including younger patients for prevention or older patients for correction.

Is it painful?
Injection discomfort is minimal, especially when applied with numbing agents.

Can it be used with other treatments?
Yes. It’s often combined with microneedling, lasers, or fillers for a more complete result.

Where to Buy PLINEST®

PLINEST® is available through authorized distributors and licensed medical suppliers. It must be administered by trained professionals in a clinical setting.

Order PLINEST® online on Maylips today!