What is Ellanse Filler Used For & What are the Side Effects?


Ellanse is a brand of injectable fillers that are free from potentially-harmful pyrogen and latex. Completely bioresorbable, these implants are composed of poly-e-caprolactone (PCL), a potent polyester. The PCL microspheres are homogenously suspended in a gel carrier that is made of carboxymethylcellulose (CMC), glycerin, and phosphate buffered saline.

The Ellanse brand comprises four fillers, Ellanse S, M, L, and E, which are differentiated based on their duration of action, with Ellanse S lasting for about a year and Ellanse E lasting for approximately 4 years. Ellanse is designed, manufactured and marketed by AQTIS Medical BV.


The active ingredient in Ellanse fillers, PCL microspheres, is well-known due to its strong biostimulating property. Once injected into the skin, the gel carrier instantly corrects the aesthetic imperfections via volumization, while PCL microspheres increase the restoration and production of collagen fibers. The corrected regions appear volumized and radiant.

Ellanse implants are commonly used to treat the following cosmetic indications:

  1. Deep-set facial wrinkles and creases, like nasogenian furrows and marionette lines;
  2. Inelastic skin such as on the jawline;
  3. Ill-defined facial contours like the cheekbones;
  4. Non-surgical augmentation of facial features like the nose. 


Like other dermal fillers, patients who are treated with Ellanse may develop common localized reactions such as redness, swelling, and bruising. These inflammatory reactions are mild in nature and occur as the skin recovers from the minimally invasive injections. Theese injection site responses typically resolve within a few days.

Patients should avoid partaking in strenuous physical activities for at least a day and avoid exposing the treated areas to direct sunlight for at least a week following the treatment session. However, patients are nonetheless at risk of developing adverse health reactions like induration (hardening of tissues), infections, and allergic attacks. Sometimes, these severe side effects happen due to medical errors caused by the injecting physician.

Patients must understand the risks and possible complications of Ellanse fillers prior to the procedure. They must also be educated in identifying adverse reactions so that they can obtain immediate medical attention.

Ellanse has a high safety profile and is well tolerated in most patients.