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What is The Difference Between Sculptra vs Radiesse?

May 11, 2018

Soft tissue fillers or dermal fillers are FDA-approved medical devices with proven safety and efficacy in rejuvenating ageing skin. Although hyaluronic acid-based fillers are the most popular injectable is the market, the limited duration of these fillers may leave some patients dissatisfied. Semi-permanent and permanent fillers are gaining a following because of their longer duration of effects, but they are also more inclined to cause adverse events. Aside from the type of material used, the implantation area and diffusion of the medication affect the longevity of the treatment.

Similarities and differences between Sculptra vs Radiesse

Sculptra and Radiesse are semi-permanent soft-tissue fillers that can both provide volume restoration and wrinkle reduction, but they are different in many ways. Both dermal fillers use different types of synthetic materials and they have a different mode of action. Sculptra contains Poly-L-lactic acid microsphere beads that immediately plump up the treated area, but volume correction may take 2 or more months to be fully evident. As Sculptra dissolves, it stimulates the production of new collagen, which provide additional volume.

Radiesse, on the other hand, contains calcium hydroxyapatite, a natural substance commonly found in human bones and teeth. Though it can add volume to the cheeks, chin, and jawline.

Comparison Chart

Contains Poly-L-lactic acid (PLLA)Contains Calcium hydroxyapatite (CaHA)
No skin testing requiredNo skin testing required
Non-animal derivedNon-animal derived
May last between 18 to 23 monthsMay last beyond 12 months
Use for filling nasolabial folds and other deep wrinkles, and enhancing the volume of the cheeks and templesUsed for augmenting cheek bones and jawlines, and filling hollow areas of the cheeks
Immediate resultsResults are not immediate       
Requires multiple injections before optimum outcome is seenRequires at least one injection per year
Costs less than RadiesseMore expensive