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Xeomin
Xeomin vs Dysport – Comparing Korean Toxins
Sep 9, 2024
Botulinum toxin type A injections are the most popular noninvasive cosmetic procedures in the United States, with millions of treatments performed annually. Commonly known as Botox, these injections temporarily paralyze facial muscles to reduce wrinkles and fine lines.
Xeomin and Dysport stand out among the various botulinum toxin products for their unique formulations and effectiveness. Xeomin is known for its pure formula without unnecessary proteins, while Dysport is favored for its rapid onset of action. Both offer distinct advantages, making them popular for those seeking smoother, more youthful-looking skin.
In this article, we compare Xeomin and Dysport, exploring their features, benefits, and key differences to help you determine which product may best suit your cosmetic needs.
Key Takeaways
- Xeomin and Dysport are widely used botulinum toxin treatments that effectively target facial wrinkles, offering non-surgical solutions for a smoother appearance.
- While both toxins work by relaxing muscles to reduce wrinkles, Xeomin is known for its “naked” formula without accessory proteins, whereas Dysport includes additional proteins, which may affect its distribution.
- Dysport typically acts faster, with results visible within 24-48 hours, whileXeomin may take a few days. The longevity of results also varies, with each product offering unique advantages based on individual patient needs.
- Understanding differences in formulation, onset, and duration helps medical professionals choose between Xeomin and Dysport based on specific goals, ensuring optimal outcomes.
- Despite their differences, both products are highly effective, allowing personalized treatment plans to achieve natural-looking, long-lasting results.
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Understanding Xeomin and Dysport
Xeomin is a botulinum toxin type A treatment known as the “naked” neurotoxin due to its pure formulation without complex proteins. This unique composition makes Xeomin less likely to trigger immune responses, allowing it to work effectively in reducing wrinkles by temporarily paralyzing targeted facial muscles.
Dysport is another popular botulinum toxin treatment that softens wrinkles and fine lines. Unlike Xeomin, Dysport contains accessory proteins in addition to the neurotoxin, which can affect how it interacts with the body. Dysport is known for its quick onset of action and is often preferred by patients seeking faster results.
Both Xeomin and Dysport work by inhibiting muscle contractions to smooth out wrinkles and create a youthful appearance. Despite their formulation differences, they share a common mechanism of action and are both effective in treating dynamic facial lines.
Formulation and Composition
Xeomin is known for its “naked” formulation, containing only the core neurotoxin protein without any additional complexing proteins. This pure composition potentially reduces the risk of antibody formation, which may enhance its efficacy and safety over time by preventing the body from developing resistance to the treatment.
On the other hand, Dysport includes accessory proteins along with the core neurotoxin. These added proteins can influence how the product interacts with the body, potentially affecting its effectiveness and safety. Dysport’s unique formulation may lead to slightly different outcomes than Xeomin, which could be a factor in patient and practitioner preferences.
Key Differences in Formulation and Composition
- Purity: Xeomin is considered a “pure” botulinum toxin without extra proteins, whereas Dysport includes accessory proteins.
- Antibody Formation: Xeomin’s lack of additional proteins may reduce the likelihood of antibody formation, which can influence treatment longevity.
- Formulation Impact: Dysport’s accessory proteins may affect how quickly and effectively the product works in the body.
- Efficacy and Safety: Variations in formulation can impact how each product performs, making it essential to consider these factors when selecting the best treatment.
Efficacy and Clinical Performance
Evaluating the effectiveness of Xeomin and Dysport in reducing wrinkles provides valuable insights for medical professionals. Our comprehensive analysis provides more in-depth details on their performance.
Image courtesy of Ferzli Facial Plastic Surgery
Two pivotal phase 3 clinical studies demonstrated the efficacy and safety of Xeomin (incobotulinumtoxinA) in treating upper facial lines, including horizontal forehead lines, glabellar frown lines, and lateral canthal lines. These studies included 730 adult participants and showed a significantly higher response rate for Xeomin compared to placebo at Day 301. The results indicated a rapid onset of action and high patient satisfaction.
Image courtesy of Skin MD Laser & Cosmetic Group
A study on Dysport reconstitution volumes for treating moderate to severe glabellar lines found both volumes effectively reduced wrinkles. It assessed the proportion of responders achieving at least a 1-point reduction in severity score at Day 303. Another study comparing Dysport and Botox for upper limb spasticity showed Dysport’s non-inferiority, highlighting its comparable safety and efficacy.
These studies highlight the effectiveness of both Xeomin and Dysport in wrinkle reduction, providing valuable insights for those considering these treatments.
Onset Time and Duration of Results
Xeomin generally begins to take effect within 3 to 4 days, with full results typically visible by two weeks. For medical conditions like cervical dystonia, the onset may take about a week. Individual responses can vary based on factors such as age, metabolism, and the treated area.
Xeomin is commonly used for cosmetic treatments in areas like crow’s feet and forehead lines, where precise dosing and monitoring through Xeomin before and after photos can help assess progress.
Meanwhile, Dysport is known for its faster onset, usually taking effect within 24 to 48 hours, with full results visible in about a week. This quicker response time makes it an appealing option for patients seeking faster improvements in their appearance.
Duration of Results for Xeomin and Dysport
Xeomin’s wrinkle-smoothing effects generally last 3 to 6 months, depending on factors such as metabolism and muscle strength. This longer duration makes Xeomin a preferred choice for those seeking a refreshed look without the need for frequent touch-ups.
Dysport typically provides results that last around 3 to 4 months, although some patients may experience effects that extend up to 6 months. The shorter duration compared to Xeomin may influence follow-up scheduling and patient expectations.
Conclusion
Xeomin and Dysport are widely used by healthcare professionals for their effectiveness in reducing wrinkles, each offering unique benefits due to differences in formulation and composition. While both deliver reliable results, their onset times and duration can vary, making it important for practitioners to consider these factors when choosing the most suitable option for their patients.
Understanding the distinct characteristics of Xeomin and Dysport helps ensure optimal treatment outcomes tailored to individual needs and preferences.
FAQs
1. What is Xeomin, and how does it work?
Xeomin is a botulinum toxin used to reduce wrinkles, such as crow’s feet, by injecting specific facial sites. The dosing varies based on the treatment area.
2. What are the advantages and disadvantages of using Xeomin?
Xeomin offers benefits such as visible wrinkle reduction, but potential drawbacks include possible side effects or discomfort during injection.
3. How does Dysport compare to Xeomin?
Dysport, like Xeomin, is used for cosmetic procedures but differs in reconstitution and dosing guidelines.
4. Can I see immediate results with these treatments?
Results can vary; some individuals may notice changes immediately, while others might see significant improvements over several days or weeks.
References
Comparing Neurotoxins: Botox, Dysport, Jeuveau, and Xeomin | The AEDITION. Aedit.com | Aesthetic Edit. https://aedit.com/aedition/comparing-neurotoxin-botulinum-type-a-injections-botox-dysport-jeuveau-xeomin
Botox-type Injectables, Neurotoxins. ABCS. https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/guide-botox-type-injectables/