A person receives a cosmetic injection in the forehead. They are lying down, covered with a gray towel, while a gloved medical professional administers the injection. The setting appears to be a clinic or spa.
Ellanse
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Last Updated On November 7, 2024

Ellanse vs Radiesse – How Do They Compare?

Nov 4, 2024

Over the years, experts have found that dermal fillers can significantly enhance collagen production in the skin, resulting in improved elasticity and a more youthful appearance. These treatments are gaining popularity due to their long-lasting and rejuvenating effects.

Among the options available, Ellanse and Radiesse stand out for their exceptional collagen-stimulating properties. Each product offers unique advantages with distinct formulations tailored to different aesthetic goals, making it essential to understand their differences.

In this article, we will compare Ellanse vs Radiesse, exploring their benefits, potential side effects, and expected outcomes to help you make an informed decision.

Key Takeaways

  • Ellanse uses polycaprolactone (PCL), while Radiesse contains calcium hydroxylapatite (CaHA), providing distinct benefits for different aesthetic goals.
  • Both fillers stimulate collagen, enhancing skin firmness, but Ellanse offers gradual improvements, whereas Radiesse provides quicker volume.
  • Ellanse can last up to four years, while Radiesse typically lasts 12–18 months, making Ellanse ideal for long-term results.
  • Radiesse is FDA-approved and widely accessible, while Ellanse may not be available in certain regions like the U.S.
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Understanding Ellanse and Radiesse Fillers

Ellanse and Radiesse are popular dermal fillers, each offering unique ingredients and benefits for skin rejuvenation. Ellanse uses polycaprolactone (PCL), which provides immediate volume and stimulates collagen production, with results lasting up to four years. This makes it an excellent option for those seeking durable, gradual improvements.

A patient receives filler treatment for facial rejuvenation

On the other hand, Radiesse contains calcium hydroxylapatite (CaHA) and is FDA-approved. It delivers quick and effective results with long-lasting effects. Ideal for smoothing wrinkles and enhancing hand appearance, Radiesse also promotes elasticity and firmness.

Mechanism of Action

Ellanse uses PCL microspheres suspended in a gel. Upon injection, these microspheres provide immediate volume, smoothing out wrinkles and adding structure. Over time, the PCL microspheres gradually stimulate the body’s natural collagen production. As the filler gradually breaks down, new collagen continues to support the skin, resulting in long-lasting effects—typically up to four years.

Meanwhile, Radiesse contains CaHA microspheres in a gel matrix, which immediately volumize and lift the skin upon injection, creating a firmer, smoother appearance. CaHA also promotes collagen production, but its effects last around 12 to 18 months. This makes Radiesse ideal for patients seeking noticeable yet moderately durable results.

Treatment Applications

Ellanse and Radiesse fillers serve unique purposes in skincare treatments. They each shine in different areas, offering solutions for aging signs like wrinkles and loss of volume.

A woman receives filler treatment for skin rejuvenation

Common Uses for Ellanse Fillers

  • Sculpt areas like cheeks and jawlines.
  • Enhances skin elasticity for a tighter appearance.
  • Smooth wrinkles around the mouth and forehead.
  • Reduces dark circles and bags under the eyes.
  • Getting Ellanse hands treatment help rejuvenate this area by addressing wrinkles, volume loss, and dryness.

Common Uses for Radiesse Fillers

  • Smooth facial lines and wrinkles.
  • Enhance cheek volume, making cheeks look fuller.
  • Improve jawline definition.
  • Correct volume loss on the back of hands.
  • Lift and contour the face without surgery.
  • Reduce marionette lines around the mouth.
  • Soften nasolabial folds, also known as smile lines.
  • Fill in deep scars on the face from acne or injury.
  • Support other facial rejuvenation treatments by providing a base layer of volume.

Effectiveness and Longevity

An article published in the Aesthetic Plastic Surgery journal reviews Ellanse as a biodegradable collagen stimulator. It highlights Ellanse’s superior aesthetic results, safety, and naturalness, making it a preferable choice for facial injections.

A woman with smooth, glowing skin

Radiesse, on the other hand, has been extensively studied for its efficacy and safety in treating nasolabial folds. Clinical trials have shown that it provides lasting improvement with minimal adverse effects. Another study published in the Aesthetic Surgery Journal confirmed sustained improvement and no long-term adverse events with Radiesse use.

When evaluating longevity, each filler addresses different needs. Ellanse can last up to 4 years thanks to its unique polycaprolactone (PCL) formulation, perfect for gradual facial shaping. In comparison, Radiesse typically lasts around 12 to 18 months, but its collagen-stimulating properties can enhance the results, leading to longer-lasting improvements over time.

Patient Satisfaction and Safety

People often feel happy with the results from both Ellanse and Radiesse fillers. Safety for each treatment matters greatly, so knowing what to expect can help them choose wisely.

On Ellanse

Ellanse before and after comparison

Image Courtesy of Yorkshire Skin Centre

The patient underwent a full face rejuvenation with 6ml of Ellanse. Three months after treatment, her natural collagen enhanced structural support, resulting in a subtle, refreshed appearance without visible filler.

On Radiesse

Radiesse before and after comparison

Image Courtesy of Rejorvenate & Co.

The patient received a diluted Radiesse treatment on her lower face. Photos taken before and 45 days post-treatment show improved smoothness in her marionette lines and nasolabial folds, with natural results continuing to develop for 4-6 months.

Making Informed Decisions

When choosing between Ellanse and Radiesse fillers, there are several factors to consider to ensure the best fit for your aesthetic goals and lifestyle:

  • Longevity: Ellanse offers results that last up to four years, while Radiesse lasts around 12 to 18 months.
  • Treatment Goals: Radiesse provides immediate firmness, while Ellanse supports gradual, long-term skin quality improvements.
  • Maintenance: Ellanse requires fewer touch-ups, whereas Radiesse allows for more frequent, minor adjustments.

A consultation with a qualified provider is essential for choosing the right filler. During the appointment, your provider will evaluate your skin needs, discuss desired outcomes, and help guide you toward the option that best aligns with your goals, skin type, and lifestyle. This personalized approach ensures a treatment plan tailored to achieve natural, satisfying results.

Conclusion

Ellanse and Radiesse fillers each offer unique benefits for facial shaping. While Ellanse provides results lasting up to four years, it may not be available in major parts of the United States. Radiesse is widely accessible and delivers quick, effective results. Both fillers stimulate collagen for firmer skin but use distinct ingredients. Consult with a qualified provider to determine the best option for your needs.

FAQs

1. What are the differences between Ellanse and Radiesse?

Ellanse and Radiesse are both collagen-stimulating fillers but differ in formulation and longevity. Ellanse uses PCL, which can last up to four years and offer gradual collagen enhancement. Radiesse contains CaHA, providing quicker, moderate-term results that typically last 12 to 18 months.

2. Is Ellanse FDA-approved?

No, Ellanse is not FDA-approved, which may limit its availability in the U.S. However, it is approved in many other regions globally.

3. Are there side effects associated with using Ellanse on the forehead?

Yes, mild side effects like swelling, redness, or tenderness may occur but typically subside within a few days.

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References

Song, L., Qiu, H., Chen, Z. et al. Injectable hyaluronate/collagen hydrogel with enhanced safety and efficacy for facial rejuvenation. Collagen & Leather 6, 21 (2024). https://doi.org/10.1186/s42825-024-00165-7 

Yi K, Waranaree Winayanuwattikun, Kim S, et al. Skin boosters: Definitions and varied classifications. Skin research and technology. 2024;30(3). doi:https://doi.org/10.1111/srt.13627