BOTOX® 100u (Polish)

BOTOX® 100u is a botulinum toxin type A injectable used for both medical and aesthetic applications. It works by blocking the release of acetylcholine, leading to temporary muscle paralysis. This reduces the appearance of wrinkles and treats conditions like muscle spasticity, migraines, and hyperhidrosis. It is administered via intramuscular injection in precise doses. The effects typically last between 3 to 6 months, requiring repeated treatments for sustained results. Proper dilution and administration techniques are essential to maximize efficacy and minimize adverse effects.

Key Features:

• Active Ingredient: OnabotulinumtoxinA, a purified neurotoxin.
• Duration: Effects last 3-6 months, depending on treatment area and dosage.
• Applications: Used for both cosmetic (wrinkle reduction) and therapeutic (muscle disorders, migraines) purposes.

BOTOX® 100u comes in a single-use vial containing a vacuum-dried powder for reconstitution. The vial is sealed with a tamper-evident holographic film and labeled with a unique serial number. Each package includes detailed instructions for dilution and administration.

Ingredients:

• Active Component: OnabotulinumtoxinA (100 units per vial).
• Excipients:
  • Human albumin (0.5 mg/mL) – stabilizes the solution.
  • Sodium chloride (0.9 mg/mL) – maintains isotonicity.

BOTOX® 100u is used for a variety of cosmetic and medical indications.

Approved Indications:

• Aesthetic Use:
  • Glabellar lines (frown lines) – 20 units per session.
  • Lateral canthal lines (crow’s feet) – 24 units per session.
  • Forehead wrinkles – 20 to 40 units per session.
• Medical Use:
  • Chronic migraines – 155-195 units injected across head and neck.
  • Hyperhidrosis (excessive sweating) – up to 50 units per axilla.
  • Muscle spasticity and dystonia – dose varies based on muscle group.

Contraindications:

• Hypersensitivity to botulinum toxin or any excipient.
• Active infection at the injection site.
• Neuromuscular disorders (e.g., myasthenia gravis, Lambert-Eaton syndrome).

Common Side Effects:

• Mild: Headache (9%), eyelid ptosis (3%), local pain.
• Moderate: Brow ptosis (2%), eyelid edema (1%), muscle weakness.
• Severe (rare): Dysphagia, respiratory issues, cardiovascular complications.

BOTOX® 100u is administered intramuscularly in a diluted form using preservative-free 0.9% sodium chloride. Each injection site and dose should follow precise medical guidelines.

Administration:

• Facial Wrinkles:
  • Glabellar lines: 0.1 mL (4 units) per site, total: 20 units.
  • Forehead lines: 0.1 mL (4 units) per site, total: 40 units.
  • Crow’s feet: 0.1 mL (4 units) per site, total: 24 units.
• Medical Uses:
  • Migraine: 31 injections (total: 155-195 units).
  • Hyperhidrosis: Multiple injections, up to 50 units per area.
  • Spasticity: Individualized doses depending on severity.

Storage Guidelines:

• Unopened vials: Store at 2° to 8°C (refrigerated).
• After reconstitution: Use within 24 hours, keeping at 2° to 8°C.
• Avoid freezing and excessive shaking to maintain potency.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.