Mazdutide 10mg

Description

Strength: 10mg
CAS: 2259884-03-0
Chemical Formula: C₂₁₀H₃₂₂N₄₆O₆₇
Molecular weight: 4563.06 g/mol
Peptide Sequence: His-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Glu-Lys-Lys-Ala-Lys-{AEEA-AEEA-γGlu-Nonadecanoic acid}-Glu-Phe-Val-Glu-Trp-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-NH2
Synonyms: IBI-362 (or IBI362) LY-3305677 (or LY3305677)
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.

Mazdutide (10mg) is a synthetic long-chain peptide developed for laboratory research involving metabolic and endocrine signaling. The Mazdutide peptide is a 33-amino acid synthetic peptide conjugated to a C20 fatty diacid moiety, designed to engage multiple metabolic regulatory pathways, with an approximate molecular weight of ~4,563 Daltons and molecular formula C₂₁₀H₃₂₂N₄₆O₆₇. The peptide sequence contains one non-coded amino acid residue (Aib) at position 2, a modification associated with improved stability during experimental observation.

This product is supplied as a high-purity lyophilized powder in a sealed research vial to support accurate handling and reproducible laboratory use. Mazdutide has been studied for its role in metabolic regulation, particularly in experimental models examining energy balance, coordination of hormonal signaling, and systemic metabolic responses under controlled conditions.

• Supplied as a 10 mg lyophilized vial for controlled laboratory reconstitution
• Studied as a GLP-1R/GCGR dual agonist in metabolic and endocrine signaling research
• Designed to support stability during experimental handling and storage
• Suitable for in vitro and preclinical research environments
• Secure vial packaging to help maintain peptide integrity
• Commonly sourced by laboratories that buy Mazdutide peptide
• For laboratory research use only

Mazdutide is being investigated as a dual GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR) agonist that modulates metabolic signaling systems involved in energy regulation, with reported binding affinity to human GCGR (Kᵢ = 17.7 nM) and GLP-1R (Kᵢ = 28.6 nM). The C20 fatty acid conjugation enables albumin binding and extended half-life in experimental models, supporting sustained exposure during laboratory evaluation.

In research settings, Mazdutide is used to examine how peptide-based signaling coordinates communication between metabolic organs and endocrine pathways. Research applications often focus on metabolic signaling patterns, hormonal coordination, and energy-utilization models under controlled experimental conditions, without extending into receptor-level clinical or therapeutic investigation.

Published research on Mazdutide describes a range of experimental dosing protocols that vary by study design, species, and exposure duration. Dosing is calculated relative to model parameters and administered under strictly controlled laboratory conditions.

Observed effects in research settings are reported as measurable changes in metabolic signaling markers and hormonal response patterns, rather than clinical or therapeutic outcomes. Laboratories that order Mazdutide peptide reference these findings when comparing signaling efficiency, duration, and stability across metabolic research models.

Mazdutide (10mg) should be stored in its lyophilized form at 2–8°C for short-term use, or at -20°C or below for long-term storage, protected from light and moisture to preserve peptide stability. Once reconstituted, solutions should be stored at 2–8°C and used within the timeframe defined by the research protocol, commonly within 2–4 weeks.

This product is intended for use by trained professionals in controlled research environments and should be handled in accordance with standard laboratory safety procedures.

References

https://www.nature.com/articles/s41467-023-44067-4

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00235-X/fulltext

https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1654506/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC10438375/

https://pubmed.ncbi.nlm.nih.gov/39696983/

Compliance Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use.