MGF IGF-1Ec 5mg

Description

Strength: IGF-1Ec
CAS: N/A
Chemical Formula: C₁₂₄H₂₀₄N₄₂O₄₁S₁
Molecular weight: 2971.99 g/mol
Peptide Sequence: Tyr-GIn-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-GIn-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-Cys
Synonyms: Mechano Growth Factor C-terminal
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.

MGF IGF-1Ec (5mg), commonly referred to as the MGF peptide (Mechano Growth Factor), is a research-grade splice variant of insulin-like growth factor-1 (IGF-1). This isoform is endogenously expressed in response to mechanical muscle stress or injury and has been widely examined in preclinical research models focused on muscle signaling and tissue adaptation.

Unlike systemic IGF-1, MGF (IGF-1Ec) contains a distinct E-peptide sequence, which is believed to favor localized autocrine and paracrine signaling rather than prolonged systemic activity. As a result, it is frequently studied in muscle repair, satellite cell activation, and early-phase regenerative signaling research.

This product is supplied as a lyophilized powder in sterile, sealed vials and is intended exclusively for laboratory research use.

MGF IGF-1Ec is valued in experimental settings for its distinct biological behavior compared with systemic IGF-1 variants. While promising effects have been reported in research models, it is not approved for clinical use.

• Single-Peptide Composition: Contains purified MGF (IGF-1Ec) for targeted mechanistic studies
• High Purity & Stability: Supplied as a pharmaceutical-grade lyophilized powder
• Localized Growth Signaling: Studied for site-specific muscle repair signaling rather than systemic growth effects
• Primary Research Areas: Muscle regeneration, satellite cell activation, and post-injury signaling
• Preclinical Focus: Investigated primarily in mechanotransduction and muscle injury models
• Storage Integrity: Store lyophilized material at 2–8 °C, protected from light and moisture
• Regulatory Notice: For laboratory research use only; not for human or veterinary application
• Ordering Information: Researchers may buy MGF peptide from authorized laboratory suppliers

MGF IGF-1Ec is a locally acting growth factor implicated in early muscle repair signaling. In contrast to circulating IGF-1, MGF is believed to act transiently at the site of mechanical strain, supporting rapid cellular responses following tissue damage.

Research findings indicate that MGF may:

• Stimulate satellite cell activation, a key event in muscle regeneration
• Influence early protein synthesis pathways during tissue repair
• Exhibit a short biological half-life, making it useful for studying transient growth signaling

These characteristics make the MGF peptide a valuable experimental tool for laboratories that order MGF peptide to investigate muscle biology and adaptive cellular responses.

Research involving MGF IGF-1Ec employs model-specific dosing strategies, often using localized administration in animal or in vitro systems. Concentrations and exposure durations vary widely depending on study design.

Reported experimental observations include:

• Increased satellite cell activity
• Enhanced localized cellular proliferation
• Activation of early muscle repair signaling pathways

All findings originate solely from laboratory and animal research. There is no established safe or effective dosage for human use.

Proper handling and storage are essential to preserve peptide integrity and ensure reliable experimental outcomes.

• Unreconstituted: Store lyophilized vials at 2–8 °C, protected from light and moisture
• After Reconstitution: Refrigerate and minimize freeze–thaw cycles
• Stability: Use reconstituted solutions within a protocol-defined timeframe to maintain consistency

This product is intended solely for controlled laboratory research environments.

References

https://pubmed.ncbi.nlm.nih.gov/24146828/

https://academic.oup.com/endo/article/151/3/865/2456460

https://pmc.ncbi.nlm.nih.gov/articles/PMC5501366/

https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2015.00283/full

Compliance Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use.