MOTs-C 20mg

Description

Strength: 20mg
CAS: N/A
Chemical Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular weight: 2174.64 g/mol
Peptide Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Synonyms: Mitochondrial peptide, Mitochondria-derived peptide
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.

MOTS-c peptide (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide studied for its role in metabolic signaling, cellular stress adaptation, and mitochondrial–nuclear communication. Unlike conventional peptides encoded by nuclear DNA, MOTS-c originates from mitochondrial DNA, making it a unique model for investigating intracellular energy regulation and adaptive responses under metabolic stress.

MOTS-c (20mg) is supplied as a high-purity, lyophilized powder in sterile, sealed vials for laboratory research use only. Researchers examining mitochondrial signaling pathways may choose to buy MOTS-c peptide for controlled experimental applications.

• Mitochondrial-Derived Peptide: Encoded within mitochondrial DNA, supporting unique intracellular signaling research
• High Purity & Stability: Pharmaceutical-grade, lyophilized peptide with verified sequence integrity
• Research-Optimized Format: Supplied in sterile vials requiring reconstitution with laboratory-grade diluent
• Primary Research Areas: Studied in metabolic regulation, insulin signaling, and cellular stress response
• Preclinical Focus: Investigated in cell culture and animal models involving muscle, metabolic tissue, and mitochondrial function
• Storage Integrity: Store at 2–8 °C; reconstituted solutions should be refrigerated and used promptly
• Regulatory Notice: Intended strictly for laboratory research use only
• Ordering Information: Researchers may order MOTS-c peptide from authorized research suppliers

MOTS-c has been studied for its ability to translocate to the nucleus under metabolic stress, where it may influence gene expression related to energy balance and cellular adaptation. Research suggests involvement in pathways associated with glucose utilization, mitochondrial efficiency, and stress-activated signaling cascades.

Preclinical investigations focus on how MOTS-c may contribute to adaptive responses during metabolic challenge, exercise-related stress, and mitochondrial dysfunction. All findings remain limited to in vitro and animal research models, with no validated clinical applications.

In published cellular and animal studies, MOTS-c has been evaluated at microgram-level doses, with protocols varying by study design, administration route, and target tissue.

Reported research observations include:

• Activation of metabolic stress-response pathways
• Modulation of insulin-related signaling markers
• Enhanced mitochondrial adaptive signaling

These observations are derived exclusively from preclinical research. There is no established safe dosage or administration protocol for human use.

Proper storage and handling are essential to preserve peptide stability and research reliability.

• Lyophilized Storage: Store at 2–8 °C, protected from light and moisture
• After Reconstitution: Refrigerate at 2–8 °C and use within a research-appropriate timeframe
• Handling Practices: Minimize freeze–thaw cycles and use aseptic technique at all times
• Safety Notice: MOTS-c has not been clinically evaluated, and human safety data are unavailable. This product must be used only in controlled laboratory research settings.

References

https://pmc.ncbi.nlm.nih.gov/articles/PMC4350682/

https://www.nature.com/articles/s41467-020-20790-0

https://www.sciencedirect.com/science/article/pii/S1550413118303905

https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1120533/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC5116416/

https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1602271/full

Compliance Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use.