REVANESSE® PURE™ with Lidocaine

Description

Name:REVANESSE® PURE™ with Lidocaine
Manufacturer: Prollenium Medical Technologies Inc
Active Substance(s): HYALURONIC ACID, MANNITOL
Strength: 14mg/ml
Pack Size: 1ML – 2 Pre-Filled Syringes
Package Content: 2 x 1.2ml Pre-Filled Syringes, 4x 30G 1⁄2″ Needles

REVANESSE® PURE™+ with Lidocaine is a cross-linked hyaluronic acid (HA) dermal filler formulated to improve facial rhytides and correct lipoatrophy through intradermal injection. With a concentration of 14 mg/mL HA and 0.3% lidocaine, this filler provides a gentle, hydrating solution suitable for superficial lines and overall skin revitalization. It is especially ideal for treating fine wrinkles and delicate areas requiring a soft, smooth gel texture with minimal swelling or irritation.

Manufactured by Prollenium Medical Technologies Inc., the product features a transparent, colorless, and odorless synthetic HA gel, offering a moderate implantation longevity of around 4 weeks depending on the injection depth and location. It is intended for professional use by qualified physicians trained in dermal filler administration. The product is well tolerated, with a strong safety profile and self-limiting, mild side effects.

• Contains 14 mg/mL of cross-linked hyaluronic acid and 0.3% lidocaine
• Indicated for intradermal treatment of facial lines and volume loss
• Offers hydration and smoothing with a 4-week average duration

Revanesse® Pure™+ is presented in sterile, single-use pre-filled syringes for safe, convenient clinical use. The packaging ensures hygiene, dosage accuracy, and sterility for professional medical environments.

Packaging includes:

• • Two 1.2 mL pre-filled syringes
  • Up to two 27G sterilized needles
  • Glass syringes with Luer-lock connections and tamper-evident seals
    

Key ingredients:

• • Hyaluronic Acid (14 mg/mL) – cross-linked for moderate duration and hydration
  • Lidocaine Hydrochloride (0.3% w/w) – reduces injection discomfort
  • Phosphate buffered saline – ensures pH balance and isotonicity

Revanesse® Pure™+ is indicated for the correction of superficial facial wrinkles and soft tissue volume loss due to lipoatrophy. It is particularly suited for fine lines and superficial dermal implantation, providing hydration and a rejuvenating effect with minimal structural volume.

Primary indications:

• • Treatment of facial rhytides and fine wrinkles
  • Correction of mild lipoatrophy
  • Skin hydration and smoothing
    

Contraindications:

• • Allergy to lidocaine, hyaluronic acid, or gram-positive bacterial proteins
  • Pregnant or breastfeeding patients
  • Individuals under 18 or over 65 (safety not established)
  • Injection in or near eye contours, blood vessels, or areas with permanent fillers
  • Patients with autoimmune disorders, inflammatory skin diseases, active infections, coagulation disorders, or multiple severe allergies
    

Side effects:

• • Mild injection-site reactions: redness, swelling, pain, itching, tenderness, or discoloration (lasting ≤1 week)
  • Nodules or induration at the site
  • Rare: glabellar necrosis, abscesses, granulomas, hypersensitivity reactions (<1 in 1500 cases), usually resolving in ~2 weeks
    

Revanesse® Pure™+ must be administered by healthcare professionals with training in soft tissue filler injections. Safe technique and proper patient selection are essential to reduce adverse events and ensure optimal aesthetic outcomes.

Administration guidelines:

• • Let the syringe reach room temperature for 30 minutes
  • Disinfect treatment area under sterile conditions
  • Inject slowly with minimal pressure
  • Avoid areas with high vascularity (e.g., glabella, nasal region)
  • If blanching occurs, stop injection and massage until normal skin color returns
  • Expel a drop from the needle tip before injecting to ensure smooth flow
  • Do not reuse the syringe or needle
    

Precautions:

• • Avoid contact with benzalkonium chloride and quaternary ammonium compounds
  • Do not treat areas with other filler products or permanent implants
  • Post-treatment: Avoid heat, cold, UV exposure, and touching the treated area for 12 hours
  • Limit total annual lidocaine dose to 20 mL per 60 kg of body weight
    

Storage instructions:

• • Store between 2°C and 25°C
  • Protect from freezing and direct sunlight
  • Use product before the expiry date printed on the packaging
    

Revanesse® Pure™+ with Lidocaine is an excellent solution for clinicians seeking a mild yet effective filler for facial rejuvenation, offering hydration, smoothing, and short-term correction with minimal discomfort and downtime.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.