STYLAGE® L BI-FLEX® with Lidocaine

Description

Name: STYLAGE® L BI-FLEX® with Lidocaine
Manufacturer: Vivacy
Active Substance(s): CROSS-LINKED HYALURONIC ACID (HA), MANNITOL, LIDOCAINE
Strength: 24mg/g HA, 9mg/ml Mannitol, 3mg/ml Lidocaine
Package Content: 2 x 1ml Pre-Filled Syringes, 4 x 30G ½ Needles

STYLAGE® L BI-FLEX® with Lidocaine is a cross-linked hyaluronic acid injectable filler developed by Laboratories VIVACY, France, for licensed aesthetic professionals treating deep wrinkles, facial contour deficiencies, and moderate-to-severe volume loss. Formulated with 24mg/g hyaluronic acid, 9mg/mL mannitol, and 3mg/mL lidocaine, this STYLAGE® dermal filler combines IPN-Like Technology™ with the BI-FLEX® rheological profile for smooth integration and controlled injection performance. Supplied as 2 × 1mL prefilled syringes, it is commonly indicated for nasolabial folds and marionette lines. Practitioners seeking sourcing information may contact Maylips support team for guidance.

• Strength: 24mg/g HA | 9mg/mL Mannitol | 3mg/mL Lidocaine
• Active Ingredient: Hyaluronic acid (cross-linked) 24mg/g; Mannitol 9mg/mL; Lidocaine 3mg/mL
• Dosage Form: Injectable gel — 2 × 1mL prefilled syringes + 4 x 27G 1/2″ needles
• FDA Approval Date: STYLAGE® is NOT FDA-approved. The product carries CE marking for European Union markets only. Practitioners in the U.S. should be aware that STYLAGE® products are not legally marketed for clinical use in the United States.
• Molecular Type: Cross-linked hyaluronic acid (IPN-Like Technology™)
• Intended Use: Deep wrinkle correction, volume restoration, facial contouring — for licensed aesthetic professionals
• Brand: STYLAGE®
• Country of Origin: France
• Manufacturer: Laboratories VIVACY (Paris, France)

STYLAGE L BI-FLEX with Lidocaine combines three core elements into a single injectable gel matrix to maximize structural integrity, treatment longevity, injection control, and patient comfort.

Core Differentiators & Technology

• IPN-Like Technology (Interpenetrating Polymer Network): Features two interlocked hyaluronic acid polymer networks. This unique configuration improves gel cohesivity and elasticity, helping the filler resist deformation under dynamic facial movements.
• BI-FLEX Rheological Profile: Engineered for optimized flow and tissue integration. It provides practitioners with exceptional injection control, enabling smooth, uniform, and controlled extrusion during placement.
• Mannitol (9mg/mL) for Longevity: Acts as a powerful free radical scavenger that limits oxidative degradation post-implantation. By protecting the hyaluronic acid from early breakdown, mannitol helps extend clinical durability.
• Integrated Lidocaine (3mg/mL): Modulates pain signaling directly during the procedure, improving patient comfort and tolerance without requiring a separate anesthetic step.

Clinical Longevity & Results

• Duration: Results typically remain visible for 12 to 18 months.
• Variables: Actual longevity varies based on individual metabolism, skin type, lifestyle, injection depth, and the specific treatment area.

STYLAGE fillers carry a CE mark for authorized use within the European Union. Practitioners must independently verify local regulatory compliance and licensing status prior to procurement or clinical use in the United States or other international jurisdictions.

STYLAGE® L BI-FLEX® with Lidocaine is indicated for deep wrinkle correction, facial volume restoration, and contour enhancement in adults treated by qualified medical professionals. Common treatment areas include:

• Nasolabial folds and marionette lines
• Cheek and midface volumization
• Chin and jawline contouring

The product is typically placed in the mid-to-deep dermis or subcutaneous plane, with injection depth selected based on tissue quality, patient anatomy, and correction goals. Patient suitability depends on the patient’s skin condition, prior filler history, and any contraindications, including known hypersensitivity to hyaluronic acid or amide-type anesthetics. Aseptic technique is mandatory; practitioners should avoid intravascular injection and be prepared to manage vascular complications.

Cross-linked hyaluronic acid binds and retains water within dermal tissues, producing immediate volumization and wrinkle correction after implantation. IPN-Like Technology™ enhances gel cohesivity and resistance to mechanical stress through interlocked polymer networks, thereby providing more prolonged tissue support than some conventional cross-linked fillers.

Mannitol provides additional stability by scavenging free radicals generated during inflammatory and metabolic processes, potentially slowing enzymatic breakdown of hyaluronic acid and supporting longer-lasting outcomes. Lidocaine 3mg/mL within the gel matrix modulates pain signaling during injection without requiring a separate anesthetic procedure. Like all hyaluronic acid fillers, STYLAGE® L BI-FLEX® with Lidocaine is fully reversible through hyaluronidase administration if correction or emergency dissolution is required.

• Practitioner Requirements: Injections should be performed exclusively by trained medical professionals with verified expertise in facial anatomy and advanced injectable procedures.
• Injection Depth: Optimal placement is within the mid-to-deep dermis or the subcutaneous plane, determined by the specific anatomical region and the severity of volume loss.
• Injection Techniques: Common approaches include linear threading, fanning, and cross-hatching. Technique selection depends on the treatment zone and the desired aesthetic outcome.
• Post-Procedure Care: Patients must avoid direct sun exposure, saunas, and extreme temperatures until transient redness and swelling have fully resolved.
• Expected Recovery: Localized bruising at the injection site is common and typically resolves spontaneously within a few days.

Most adverse effects are mild to moderate and resolve within a few days without intervention.

Common Side Effects

• Redness, swelling, and bruising at the injection site
• Tenderness and mild discomfort
• Temporary firmness within the treated area

Recovery time may vary depending on the treatment area, injection depth, and factors such as skin type.

Serious Adverse Events

Although rare, serious complications may occur, including vascular occlusion, skin necrosis, delayed inflammatory nodules, and visual disturbance. STYLAGE® L BI-FLEX® with Lidocaine injection should only be administered by professionals trained in vascular complication recognition and emergency management, including hyaluronidase use. Practitioners should screen for hypersensitivity to amide-type anesthetics before treatment.

Legal & Regulatory Status

STYLAGE® L BI-FLEX® with Lidocaine is manufactured in France by Laboratories VIVACY and carries CE marking for professional aesthetic use within applicable European markets. Current FDA approval status and regional regulatory requirements should be independently verified before procurement or clinical use. Practitioners who wish to buy dermal fillers or buy STYLAGE® may contact Maylips support team for sourcing information and documentation support.

For sourcing guidance, contact Maylips support team.

Regulatory information current as of mid 2026. Practitioners should confirm local regulatory status before sourcing.