Thymosin Alpha-1

Description

Strength: 10mg
CAS: 62304-98-7
Chemical Formula: C₁₂₉H₂₁₅N₃₃O₅₅
Molecular weight: 3108.3 g/mol
Peptide Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
Synonyms: Thymalfasin
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.

Thymosin Alpha-1 peptide is a synthetic version of a naturally occurring peptide found in the thymus, composed of 28 amino acids and with a molecular weight of approximately 3,100 Da. It has been extensively studied for its potential role in immune system regulation and cellular responses to stress.

This peptide is supplied in a lyophilized (freeze-dried) form, ensuring stability for transportation and long-term storage. Researchers who buy Thymosin Alpha-1 for research purposes commonly use it in studies related to immune function and cell signaling pathways. It is available in convenient 10 mg vial formats for easy reconstitution and precise experimental use.

• High Purity: ≥99% purity, verified by HPLC and MS, ensuring reproducible and reliable research outcomes.
• Lyophilized Form: Supplied as a lyophilized powder, which maintains stability and allows for flexible reconstitution.
• Immune System Research: Frequently used in studies investigating immune modulation, T-cell activity, and cytokine signaling.
• Sterile Packaging: Packaged in sealed vials to prevent contamination and ensure consistent peptide integrity.
• Easy Reconstitution: Designed for straightforward reconstitution with standard laboratory buffers.
• For Research Use Only: Intended exclusively for controlled laboratory studies and not for clinical use.

Thymosin Alpha-1 is primarily studied for its role in immune system modulation. It is believed to influence T-cell activity and cytokine production, both of which are essential for immune responses. Research has explored its potential to enhance cellular activity and improve responses to stressors, such as infections or environmental changes.

Studies often focus on how Thymosin Alpha-1 interacts with the immune system, specifically in the regulation of immune cell functions, inflammatory responses, and immune surveillance. Researchers are also examining its effects in models related to autoimmune conditions and aging, making it a valuable tool in immunology research.

Dosing of Thymosin Alpha-1 for research varies depending on the experimental design. Clinical studies typically use doses ranging from 1 mg to 16 mg, depending on the model and research objectives. The peptide is commonly administered via subcutaneous injection, with protocols tailored to specific study needs.

In research, observed outcomes often include changes in immune markers, cytokine levels, and cellular immune responses. These studies help provide valuable insights into how the Thymosin Alpha-1 peptide affects immune system function and cellular communication. Please note that all dosing information is based on controlled experiments and should not be considered as clinical guidance.

Proper storage and handling are crucial for maintaining the integrity of Thymosin Alpha-1 peptide. The following guidelines are recommended:

• Lyophilized Powder: Store at -20°C or lower for long-term storage.
• Reconstituted Solution: After reconstitution, store at 2–8°C and use within 2–7 days depending on preparation.
• Handling: Reconstitute using sterile water or PBS. Use sterile equipment and aseptic technique during handling.
• Protective Equipment: Always wear appropriate laboratory protective gear, including gloves and lab coat.
• Disposal: Follow institutional guidelines for the disposal of unused or contaminated samples.

References

https://pmc.ncbi.nlm.nih.gov/articles/PMC7747025/

https://www.sciencedirect.com/topics/medicine-and-dentistry/thymosin-alpha1

https://academic.oup.com/ajhp/article-abstract/58/10/879/5149632

https://www.sciencedirect.com/science/article/pii/S0196978110003384

Compliance Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use.