DEPO-PROVERA®

Description

Name:DEPO-PROVERA®
Manufacturer: Pfizer
Active Substance(s): MEDROXYPROGESTERONE ACETATE
Strength: 150mg/ml
Pack Size: 1-1ml prefilled syringe
Accessories: 1 x 1ml Pre-Filled Syringe

CROMA PhilArt EYE is a biorevitalizing injectable treatment designed to improve skin quality, elasticity, and hydration in the periorbital area. It is formulated with polynucleotides highly purified technology (PN-HPT®) at a 15 mg/2 ml concentration, stimulating fibroblast activity without causing excessive inflammation or edema. This treatment helps reduce fine lines, wrinkles, and sagging, making the eye contour appear refreshed and rejuvenated. Clinical studies confirm over 90% patient satisfaction with visible improvements in skin texture, firmness, and brightness​.

Key Features:

• Low-Concentration Polynucleotides (PN-HPT®) – Stimulates fibroblast activity, improving skin elasticity and hydration.
• Designed for the Eye Area – Safe and effective for thin, delicate periocular skin with minimal swelling or downtime.
• Synergistic Skin Priming Effect – Can be used alone or combined with other aesthetic treatments like laser, fillers, and microneedling​.

PhilArt EYE is packaged in a sterile, pre-filled syringe to ensure hygienic and precise application. Each syringe contains 2 ml of injectable solution, specifically formulated for sensitive skin areas.

Packaging Details:

• Pack contains: 1 x 2 ml pre-filled syringe.
• Needles included: 2 x 30G ½ (13 mm needles) for fine, precise injections.
• Injection depth: Intradermal, ensuring optimal delivery to target fibroblast activation​.

Ingredients:

• Polynucleotides Highly Purified Technology (PN-HPT®) – 15 mg/2 ml concentration, stimulating collagen and elastin production.
• Buffered saline solution – Maintains isotonic balance for skin compatibility​.

PhilArt EYE is indicated for biorevitalization of the periorbital area, addressing signs of aging and skin laxity. It helps refresh tired-looking eyes, improve skin structure, and enhance overall skin quality.

Indications:

• Treatment of fine lines, wrinkles, and crow’s feet in the eye contour area.
• Biorevitalization of delicate skin, including the eyebrow arches and sensitive areas.
• Preparation of the skin before other aesthetic treatments (lasers, radiofrequency, fillers, chemical peels, microneedling)​.

Contraindications:

• Allergy to polynucleotides or any product components.
• Active skin infections or inflammation at the treatment site.
• Autoimmune diseases or blood clotting disorders​.

Common Side Effects:

• Mild redness or swelling – Resolves within 24–48 hours.
• Temporary bruising at injection sites.
• Mild discomfort during injection, which subsides quickly​.

PhilArt EYE is administered intradermally, using a serial puncture or linear retrograde injection technique. A course of 3–4 sessions is recommended for optimal results.

Administration Guidelines:

• Injection depth: Intradermal, targeting fibroblast activation.
• Recommended dose: 1–2 ml per session.
• Treatment frequency: Every 14–21 days, for a total of 3–4 sessions.
• Injection techniques:
  • Serial puncture technique, with 0.5–1 cm spacing.
  • Linear retrograde technique, depending on treatment goals​.

Storage Instructions:

• Store between 2°C and 25°C, away from direct sunlight and heat.
• Do not freeze or expose to extreme temperatures.
• Use immediately after opening to maintain sterility and effectiveness​.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.