REVOFIL™ ULTRA

Description

Name:REVOFIL ULTRA
Manufacturer: Caregen
Active Substance(s): HYALURONIC ACID
Strength: 23mg/ml
Pack Size: 1ML – 1 Pre-Filled Syringe
Package Content: 1 x 1ml Pre-Filled Syringe, 2 x 27G (13mm) Needles

REVOFIL ULTRA is a next-generation deep touch dermal filler designed for volume restoration and deep wrinkle correction using cross-linked hyaluronic acid (HA) combined with bioactive peptides. It is particularly suitable for sculpting and volumizing thick dermal areas such as the cheeks, chin, nose bridge, jawline, and deep nasolabial folds. With 23 mg/mL of HA and a proprietary peptide complex, REVOFIL ULTRA offers high viscoelasticity, long-lasting results, and enhanced biostimulation, including collagen and endogenous HA synthesis.

The unique peptide technology—featuring Oligopeptide-72 and Oligopeptide-50—provides strong hyaluronidase inhibition (up to 90%), improving the gel’s resistance to degradation and increasing its duration in the skin. REVOFIL ULTRA is ideal for advanced contouring and volume definition with results lasting up to 12 months. Its advanced rheology supports smoother injections and high precision in mid to deep dermis or subcutaneous layers.

• 23 mg/mL cross-linked HA with peptides for volume and structure enhancement
• Inhibits hyaluronidase activity by 90%, offering superior longevity
• Designed for deep dermis or subcutaneous injection in volume-deficient regions

REVOFIL ULTRA is provided in sterile, single-use units suitable for clinical use. Each package ensures optimal product integrity and is accompanied by a needle suitable for deep dermal application.

Packaging contents:

• • One 1 mL pre-filled syringe
  • One 27G ½” needle
  • Blister-packed with full traceability and sterile labeling
    

Active ingredients:

• • Cross-linked Hyaluronic Acid (23 mg/mL) – non-animal origin, biodegradable, cohesive gel
  • Oligopeptide-72 (CG-Boostrin) – inhibits HA degradation by binding to hyaluronidase
  • Oligopeptide-50 (CG-Glamerin) – stimulates endogenous collagen and HA production
  • No PBS – replaced by free HA linked to peptides, improving stability and biological action

REVOFIL ULTRA is intended for deep dermal and subcutaneous application to correct very deep wrinkles, facial volume loss, and to reshape facial contours. It is ideal for thick-skin regions requiring structure, lift, or augmentation.

Indications:

• • Forehead lines, deep nasolabial folds, marionette lines
  • Cheeks, hollow cheek areas, chin, jawline, mandibular region
  • Lip augmentation, nose bridge contouring, and temporal volume restoration
    

Contraindications:

• • Hypersensitivity to HA or peptide ingredients
  • Pregnancy or breastfeeding
  • Active inflammatory skin conditions, autoimmune diseases, or coagulopathies
  • Use in patients under 18 years
  • Treatment near blood vessels or in areas previously filled with permanent fillers
    

Side effects:

• • Local redness, swelling, bruising, or tenderness (typically resolves in ≤7 days)
  • Nodule formation, delayed hypersensitivity, or vascular complications (rare)
  • No allergic effects were observed in a clinical study involving 56 patients with REVOFIL ULTRA

REVOFIL ULTRA should be administered only by licensed professionals with experience in deep dermal injections. It is injected into the mid to deep dermis or subcutaneous tissue using a 27G needle, with dosage and technique tailored to the treatment area.

Administration technique:

• • Allow syringe to reach room temperature before injection
  • Use 27G ½” needle for mid to deep dermal or subcutaneous injection
  • Common technique includes linear threading, fan-shaped, or cross-hatching
  • Injection volume typically 1 mL per session, depending on the treatment area
  • Gently massage post-injection to distribute product evenly
    

Treatment areas:

• • Forehead, nasolabial folds, chin, cheeks, jawline, lip borders, temples
  • Avoid areas with thin dermis unless indicated and handled with care
    

Storage instructions:

• • Store between 2°C and 25°C
  • Keep away from direct sunlight and do not freeze
  • Use before the expiry date on the packaging
  • For single use only – do not resterilize or reuse the syringe

REVOFIL ULTRA provides clinicians with a highly stable, bioactive filler for deep wrinkle correction and contouring, ensuring safe, long-lasting results enhanced by peptide-driven dermal regeneration.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.