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Active Substance(s):
Hyaluronic acid, lidocaine
20mg/ml, 3mg/ml
Pack Size:
1-2ml prefilled syringe
Package insert, 2-23G 1” needles, 2 traceability labels

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Picture shows RESTYLANE® VOLYME original box from Europe


Active Substance(s):
Hyaluronic acid, lidocaine
20mg/ml, 3mg/ml
Pack Size:
1-1ml prefilled syringe
Package insert, 2-27G needles, 2 traceability labels
Other Known Names:
USD$99 99USD


What is Restylane Volyme (Emervel Volume)?


Restylane Volyme is a cross-linked, non-animal hyaluronic acid gel used to add volume and definition in the face in areas such as the cheekbones, cheeks, and jaw. This cosmetic filler is used to sculpt the face and restore volume while supporting the skin’s natural structure to smooth the overall appearance for a more youthful effect. This product is designed with cross-linker Butanediol Diglycidyl Ether, or BDDE, to form a soft gel, and makes use of Optimal Balance Technology to allow for smooth integration into the skin. Restylane Volyme, formerly known as Emervel Volume, is manufactured by Galderma and is made using a biotechnological process of bacterial fermentation.


What is it used for?


Use this cosmetic filler for high-volume lifting and restoration in areas of the face that sculpt and contour the overall appearance of the face. The areas that benefit most from Restylane Volyme are the cheeks, chin, and jaw, as these areas best enhance the facial oval for a smoother, fuller appearance. This filler is not recommended for superficial filling, but rather for areas that require deeper added volume. As the main component of this dermal filler is hyaluronic acid, treatment also aims to hydrate the skin by restoring this naturally occurring substance that depletes with age. This results in plumper, more radiant looking skin.


How does this dermal filler work?


Restylane Volyme works to restore volume by being injected into the supraperiostic zone or subcutaneous tissue of the face. The specially designed formula allows for seamless integration with the skin resulting in renewed plumpness in the treated area. Treatment sessions typically last between 20 and 40 minutes and like many other hyaluronic acid-based products, results tend to be instant. While results are long-lasting, touch ups may be required after a certain amount of time.


How to inject


Like all dermal fillers, this product should only be administered by an experienced practitioner familiar with subcutaneous injection techniques. Cleanse the area being treated with an antiseptic before injection and use a 27G1/2” needle to administer the filler. This product contains lidocaine to numb the pain upon injection, so there should be a brief pause of a couple seconds upon initial injection in order for the anaesthetic to take effect. Injection technique and depth will vary depending on the area being treated and the volume being applied, but the product should generally be injected into the supraperiostic zone or subcutaneous tissue. Administer Restylane Volyme slowly with even pressure and massage the treatment area gently once the injection is over in order to evenly distribute the solution once injection is complete. After the procedure, recommend patients avoid using makeup for 12 hours after the injection has taken place.


How long does it last?


Duration of the effect will vary from patient to patient as longevity depends on many variables. However, patient studies have shown that results last between 6 to 9 months, with some patients experiencing lasting results for up to a year. These results will vary based on skin type, age, lifestyle, and application technique as well as the area being treated.


Is this face filler safe?


Restylane Volyme is safe to use and produces instant, long-lasting results using a non-surgical method of injection. As hyaluronic acid is a naturally occurring substance present in all living organisms, it is completely biodegradable and integrates safely with the skin. However, there are some common mild risks associated with administering this product, including the risk of infection to the injection site. For the safest results, the manufacturer cautions patients to avoid exposure to extreme temperatures after treatment until the expected inflammation has disappeared. This filler should not be used on children. As with other injection-based procedures, this product should be administered with caution on any patient using substances that could affect platelet function, such as aspirin, or any anti-inflammatory drugs.


Restylane Volyme side effects


There are some mild side effects or reactions that can be expected after treatment using Restylane Volyme. These effects tend to resolve themselves within a couple days, and you can advise patients to reach out if there are any long-lasting or unexpected effects. If a patient experiences any unexpected reactions or any effects not listed in the informational leaflet, contact the manufacturer immediately. The manufacturer also lists some contraindications, cautioning that this product should not be used: if patient has a hypersensitivity to any of the ingredients; if there is a skin infection near the injection site; if patient is susceptible to the formation of keloid scars; if patient has a history of severe allergies or anaphylactic shock; if the patient has any bleeding or autoimmune disorders; or if patient is undergoing antibiotic therapy.

The manufacturer cautions that there may also be an increased likelihood of reaction in patients who have a history of pigmentation disorder or severe scarring, or are planning on undergoing other laser treatments or chemical peeling near the injection site after treatment.


Common side effects:


  • Bruising
  • Redness
  • Pain
  • Itchiness


Less common or rare side effects


  • Skin Necrosis
  • Hypersensitivity or Allergy


Read the product pamphlet for a full list of side effects.


What is it made of?


Restylane Volyme is made primarily of hyaluronic acid in the concentration of 20mg/mL. Hyaluronic acid is a naturally occurring substance in the skin, and is completely biocompatible and biodegradable. It is metabolized slowly by the body after treatment. This filler also contains 0.3% lidocaine hydrochloride which acts as an anaesthetic to promote comfort and reduce pain during and after the procedure. Each package of Restylane Volyme comes with a 1mL prefilled syringe and 2 needles.

Ingredients: Cross-linked Hyaluronic Acid 20mg/mL, Lidocaine Hydrochloride 3mg/mL, Physiological Buffer pH 7 qs ad 1 mL.
Size: 1 pre-filled syringe of 2mL.
Manufacturer: Q-Med AB.
Origin: EUROPE.
Also Included: The box contains 2 x 23G 1" sterile needles and patient record labels. Package insert.
Storage: Store at between 2℃ and 25℃, do not freeze, keep away from direct sunlight.
Remarks: Sterile packaging.