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Polynucleotides
Polynucleotides Jowls – Reducing the Appearance of Jowls with Polynucleotides
Jan 30, 2025
Jowls, or sagging skin below the chin, are a common aesthetic concern that develops with aging. This occurs due to a decline in collagen and elastin, leading to reduced skin firmness and elasticity.
Polynucleotides offer a non-invasive solution for improving the appearance of jowls. Derived from fish DNA, these biostimulators stimulate collagen and elastin, promoting skin tightening and rejuvenation. By enhancing elasticity, polynucleotides help define the jawline with minimal recovery time.
In this article, we will explore how polynucleotide treatments can reduce jowls, offering a non-surgical alternative to traditional skin-tightening procedures.
Key Takeaways
- Polynucleotides stimulate collagen production, tightening the skin around the jowls, helping to reduce sagging and improve firmness.
- The treatment enhances skin elasticity, gradually leading to firmer, smoother skin in the jowl area with time.
- Polynucleotides provide a minimally invasive option, offering a non-surgical alternative to facelift procedures for jowl treatment.
- Visible improvements usually appear within weeks, with the best results becoming apparent after a few treatment sessions.
- In addition to addressing jowls, Polynucleotides improve skin quality by boosting hydration, texture, and overall smoothness.
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How Polynucleotides Treat Jowls
Polynucleotides effectively reduce the appearance of jowls by enhancing skin elasticity and promoting rejuvenation. These naturally occurring molecules stimulate collagen production, which is essential for maintaining firm, lifted skin. As collagen levels decline with age, sagging becomes more noticeable, particularly around the jawline.
By boosting collagen synthesis, polynucleotides help tighten and lift sagging skin while also supporting fibroblasts—the cells responsible for collagen production. This improves skin thickness, elasticity, and overall texture.
Over time, these benefits lead to a more contoured jawline and a youthful, rejuvenated appearance.
Injection Techniques
Proper injection techniques are vital for effective jowl treatment with polynucleotides. Skilled professionals ensure even distribution and target the dermal layer, where the treatment can most effectively stimulate collagen production, leading to improved skin elasticity and firmness. This precision is key to achieving optimal, long-lasting results.

- Consultation and Assessment: A consultation helps the practitioner understand the patient’s needs, assess the severity of jowl sagging, and determine the most appropriate treatment by evaluating the skin condition and facial structure.
- Local Anesthesia: To ensure a painless experience, a topical numbing agent or local anesthesia is applied to the treatment area, minimizing discomfort during the injections.
- Strategic Injection Placement: Polynucleotides are injected along the jawline in targeted areas, usually at shallow to mid-depth, to maximize collagen stimulation and effectively address sagging skin.
- Gentle Technique: A controlled, gentle technique is used to inject small doses, preventing bruising or swelling while ensuring the treatment is evenly distributed across the jowl area.
- Post-Treatment Care: Mild swelling or redness may occur after treatment, but it typically resolves quickly. Following aftercare guidelines, such as avoiding strenuous activity and sun exposure, ensures better results and faster recovery.
Proper technique and aftercare are critical to achieving the best results when treating jowls with polynucleotides.
Treatment Duration
The duration of polynucleotide treatment for jowls varies depending on skin condition and sagging severity. Typically, 2 to 3 sessions are recommended to effectively stimulate collagen production. While some may see improvements after one session, more noticeable results require multiple treatments.

Each session lasts about 30 to 45 minutes. To enhance skin tightening and achieve optimal results, follow-up sessions follow an initial treatment. Maintenance treatments can be scheduled every 6 to 12 months based on the individual’s response and desired outcome.
Results and Patient Expectations
When using polynucleotides for jowls, patients can expect gradual improvements in skin firmness and elasticity. Results typically begin to show after a few weeks as the polynucleotides’ ingredients stimulate collagen production. Visible changes usually appear after 2 to 3 treatments, with a smoother, more lifted jawline. However, the full effect may take time to develop.
It’s essential to manage expectations, as results are progressive and may require multiple sessions for the best outcome. While individual results may vary, polynucleotides offer a non-invasive solution for enhancing skin texture and reducing sagging in the jowl area.
Conclusion
Polynucleotide treatments for jowls offer a non-invasive way to improve sagging skin by stimulating collagen production. This enhances skin elasticity and tone, gradually reducing jowl appearance. Results develop over several months, with noticeable improvements after a few weeks. Multiple sessions may be needed. Seeking treatment from a skilled professional ensures optimal results for a firmer, rejuvenated jawline without surgery.
FAQs
1. What are the components of a polynucleotide?
A polynucleotide consists of a sugar molecule, a phosphate group, and a nitrogenous base (adenine, thymine, cytosine, guanine, or uracil in RNA).
2. How do polynucleotides benefit the skin?
PNs promote skin repair by stimulating collagen production, improving hydration, and reducing inflammation. They also help with skin regeneration, making the skin appear healthier and more youthful.
3. What skin concerns can polynucleotides treat?
Polynucleotides treat various skin concerns, including wrinkles, fine lines, skin laxity, acne scars, pigmentation, and overall skin texture.
4. How do practitioners administer polynucleotide injections?
Polynucleotides are commonly administered via injections or dermal fillers, though topical products incorporating PNs are available.
References
Jowls: Causes, Treatment, Prevention and More. Healthline. Published July 14, 2017. https://www.healthline.com/health/beauty-skin-care/jowls Everett JS, Sommers MS. Skin Viscoelasticity. Biological Research For Nursing. 2012;15(3):338-346. doi:https://doi.org/10.1177/1099800411434151