REVOFIL™ PLUS

Description

Name:REVOFIL PLUS
Manufacturer: Caregen
Active Substance(s): HYALURONIC ACID
Strength: 23mg/ml
Pack Size: 1ML – 1 Pre-Filled Syringe
Package Content: 1 x 1 ml Pre-Filled Syringe, 2 x 27G (13mm) Needles

REVOFIL PLUS is a next-generation sub touch dermal filler designed for moderately deep wrinkle correction and soft tissue augmentation. It combines 23 mg/mL of cross-linked hyaluronic acid (HA) with advanced peptide technology, delivering natural volume enhancement, wrinkle filling, and biostimulation in the mid to deep dermis. The formulation includes Oligopeptide-72 (CG-Boostrin) and Oligopeptide-50 (CG-Glamerin), which inhibit hyaluronidase activity by up to 90% and stimulate collagen and HA production, leading to longer-lasting and biologically active results.

REVOFIL PLUS offers both monophasic and biphasic properties, providing high viscosity, elasticity, and easy injection with smooth tissue integration. It is ideal for treating nasolabial folds, cheeks, lips, and nose bridge while enhancing skin firmness and hydration. Clinically tested with high patient satisfaction, it provides up to 12 months of visible improvement after a single treatment.

• 23 mg/mL cross-linked hyaluronic acid with peptides for moderate wrinkle correction
• Inhibits hyaluronidase activity by 90%, ensuring longer-lasting results
• Suitable for mid to deep dermal injection in lips, nasolabial folds, and facial contours

REVOFIL PLUS is supplied in sterile blister packs for professional use. Each pack contains a ready-to-use syringe and a fine-gauge needle suitable for precise intradermal or subdermal injections.

Packaging contents:

• • One 1 mL pre-filled syringe
  • One 27G ½” needle
  • Sealed in sterile packaging for single use
    

Active ingredients:

• • Cross-linked Hyaluronic Acid (23 mg/mL) – non-animal origin, biodegradable, cohesive gel
  • Oligopeptide-72 (CG-Boostrin) – inhibits degradation by binding hyaluronidase
  • Oligopeptide-50 (CG-Glamerin) – increases endogenous collagen and HA synthesis
  • Free HA linked with peptides, replacing traditional phosphate-buffered saline

REVOFIL PLUS is indicated for the treatment of moderately pronounced facial wrinkles, volume loss, and facial contour enhancement. It is especially effective in the nasolabial folds, marionette lines, lips, cheeks, and nose bridge, offering visible improvement in shape, symmetry, and smoothness.

Indications:

• • Nasolabial folds, marionette lines, lip augmentation, and cheek hollows
  • Facial contouring of chin, jawline, and nose bridge
  • Tear troughs, temples, and moderate facial asymmetry
    

Contraindications:

• • Hypersensitivity to HA, peptides, or formulation components
  • Pregnancy or breastfeeding
  • Presence of skin infections, autoimmune disorders, or coagulation defects
  • Patients under 18 years old
  • Prior use of permanent fillers in the treatment area
    

Possible side effects:

• • Redness, swelling, bruising, or itching at the injection site (resolves within 7 days)
  • Induration, nodules, or hypersensitivity reactions (rare)
  • Strong clinical safety record with no allergic reactions in a 172-patient study

REVOFIL PLUS is injected by trained professionals into the mid to deep dermis, using 27G ½” needles. Treatment techniques may vary depending on the depth and area of application and include linear threading or small bolus injections.

Injection technique:

• • Inject into the mid to deep dermis using a 27G ½” needle
  • Recommended methods include linear threading, fan, or cross-hatch techniques
  • Common treatment areas: lips, nasolabial folds, cheeks, chin, temples, and nose bridge
  • 1 mL per session, with effects lasting up to 12 months before touch-up
    

Post-injection care:

• • Gently massage treated areas to ensure uniform product distribution
  • Avoid UV exposure, extreme temperatures, and manipulation of the area for 24 hours
    

Storage instructions:

• • Store between 2°C and 25°C
    Do not freeze or expose to direct sunlight
  • Use before expiry date printed on the packaging
  • Single-use only; discard any remaining product after opening

REVOFIL PLUS offers clinicians a versatile and long-lasting filler option for moderate facial volume enhancement and wrinkle correction, delivering stable, biocompatible results supported by advanced peptide technology.

Warning! The product is intended solely for professional use in a medical environment and under professional supervision. The product is supplied to medical professionals who specialize in aesthetic medicine (plastic surgery, facial treatments) and work under individual medical licenses as aestheticians or in dedicated clinics. Unprofessional use by individuals without a medical background may lead to severe adverse effects and health harm.