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Hymovis
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Last Updated On November 22, 2024

Hymovis Injection – All About the OA Treatment

Nov 18, 2024

A systematic review published in The BMJ found that viscosupplementation, a treatment involving hyaluronic acid injection into the knee joint, offers significant pain relief for osteoarthritis patients. This minimally invasive treatment restores the joint’s natural lubrication and cushioning, making it a valuable alternative to surgical procedures.

Hymovis, a next-generation viscosupplement, is designed to alleviate knee pain caused by osteoarthritis. Its advanced gel formulation mimics the natural synovial fluid in joints, providing improved shock absorption and lubrication. Many patients experience up to six months of relief, making Hymovis a trusted option for managing OA symptoms.

In this article, we’ll explore the benefits of Hymovis injections, potential side effects, and how this treatment compares to other osteoarthritis solutions, helping you make an informed decision.

Key Takeaways

  • Hymovis injections are an FDA-approved viscosupplementation treatment designed to alleviate knee pain caused by osteoarthritis.
  • Composed of high-molecular-weight hyaluronic acid, Hymovis mimics natural synovial fluid, providing lubrication and shock absorption to the knee joint.
  • The treatment involves two injections spaced a week apart, offering pain relief and improved joint mobility for up to six months.
  • Hymovis is ideal for patients who have not responded to other treatments such as physical therapy, oral medications, or corticosteroid injections.
  • Alternatives to Hymovis include other viscosupplements (e.g., Synvisc, Durolane), non-surgical methods (e.g., PRP therapy, physical therapy), and surgical options (e.g., knee osteotomy, total knee replacement).
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What is Hymovis Injection?

Hymovis is a next-generation injectable treatment designed to relieve knee pain caused by osteoarthritis (OA). Composed of high molecular weight hyaluronan, a naturally occurring substance in the body, Hymovis mimics the properties of synovial fluid. Its gel-like consistency acts as both a lubricant and a shock absorber within the joint, reducing friction during movement and cushioning the joint from stress.

injection to relieve pain

This mechanism addresses two key issues in osteoarthritis: the loss of natural joint lubrication and reduced shock absorption, both of which contribute to pain and stiffness. By restoring these functions, Hymovis helps improve mobility, reduces discomfort, and promotes smoother joint movement.

Hymovis is often recommended for patients whose knee pain persists despite other treatments, such as physical therapy or oral pain relievers. Administered directly into the knee joint, it can provide relief for up to six months. Its FDA approval highlights its safety and effectiveness, making it a trusted option for managing OA-related knee pain.

Procedure and Treatment Protocol

Hymovis injections are an advanced treatment for knee osteoarthritis, providing lubrication and cushioning to reduce pain and improve mobility. The Hymovis prescribing information outlines essential details for healthcare professionals on dosage, administration, and safety protocols to ensure effective treatment.

knee ultrasound and injection

The treatment process typically follows these steps:

  • Evaluation: The doctor evaluates the patient’s knee condition to determine suitability for Hymovis, especially if other treatments like exercise or medication have failed to provide relief.
  • Preparation: The injection site is thoroughly cleaned to minimize infection risk. A local anesthetic may be applied to reduce discomfort during the procedure.
  • Injection: Using a sterile syringe, the doctor injects Hymovis, a gel-like hyaluronic acid solution, directly into the knee joint. Precision ensures the gel reaches the joint space for optimal results.
  • Post-Injection Care: Patients are advised to rest the knee for 24–48 hours to allow the gel to distribute evenly and integrate with the joint fluid.
  • Follow-Up: Most patients receive two injections spaced one week apart, maximizing the treatment’s effectiveness. The benefits, such as pain relief and improved mobility, can last up to six months.

Expected Outcomes and Benefits

One of Hymovis’s standout benefits is its long-lasting relief, which can extend up to six months—longer than many other viscosupplements like Synvisc or Euflexxa. This makes it particularly effective for individuals with persistent knee pain who have not responded to other treatments. In addition to pain relief, Hymovis improves knee joint flexibility, allowing patients to stay active and engage in daily tasks or sports with greater ease.

Other key benefits include:

  • Its safety profile is supported by FDA approval.
  • Suitability for patients seeking a non-surgical alternative.
  • Proven effectiveness in improving overall quality of life through better joint function.

Patient Suitability and Safety Considerations

Hymovis injections are ideal for individuals with knee osteoarthritis (OA) who have not found sufficient relief from pain relievers, exercise, or physical therapy. This FDA-approved treatment provides long-lasting pain relief of up to six months, making it especially beneficial for active individuals looking to maintain mobility and quality of life.

painful knee while walking

While generally safe, Hymovis is not suitable for everyone. Patients with infections in or around the knee, hypersensitivity to hyaluronan, or certain autoimmune conditions should avoid this treatment. Healthcare providers carefully assess the patient’s medical history and knee condition to ensure suitability and minimize risks.

Common side effects include:

  • Temporary pain at the injection site.
  • Swelling or warmth around the treated area.
  • Mild stiffness immediately after the injection, which typically resolves quickly.

Rare side effects that require medical attention may include:

  • Allergic reactions, such as redness, severe swelling, or difficulty moving the joint.
  • Infections if proper aseptic techniques are not followed.

Potential Alternatives to Hymovis Injection

For patients seeking options beyond Hymovis, a variety of treatments are available for managing osteoarthritis (OA), ranging from other viscosupplementation therapies to surgical and non-surgical approaches:

Other Viscosupplements

  • Synvisc/Synvisc-One: A single or three-injection hyaluronic acid treatment offering joint lubrication and cushioning, similar to Hymovis but with a different formulation.
  • Euflexxa: Another hyaluronic acid-based viscosupplement known for its effectiveness in managing mild to moderate OA symptoms.
  • Durolane: A single-injection treatment designed for long-term relief, often compared to Hymovis for its extended efficacy.

Non-Surgical Alternatives

  • Physical Therapy: Strengthening the muscles around the knee can reduce strain on the joint and improve mobility.
  • Oral Medications: NSAIDs (e.g., ibuprofen) can help manage pain and inflammation but may have long-term side effects.
  • Corticosteroid Injections: Provide quick, temporary pain relief by reducing inflammation in the joint.
  • Platelet-Rich Plasma (PRP) Therapy: Uses the patient’s own blood components to promote healing and reduce OA symptoms.

Surgical Options

  • Arthroscopy: A minimally invasive surgery to clean out damaged cartilage or repair minor issues in the joint.
  • Knee Osteotomy: Adjusts the alignment of the knee to relieve pressure on the affected joint.
  • Total Knee Replacement: A more invasive option for severe OA cases where other treatments have failed.

Conclusion

Hymovis injections provide a reliable, non-surgical solution for knee pain caused by osteoarthritis, offering long-lasting relief and improved mobility. Administered directly into the knee joint, this treatment is an excellent option for individuals who have not found success with other methods.

With its ability to reduce pain and enhance joint function, Hymovis enables many patients to regain their quality of life and confidently return to daily activities.

FAQs

1. How long does Hymovis provide relief?

Hymovis injections can provide relief for up to six months, making it a long-lasting option compared to other treatments.

2. How does Hymovis compare to other viscosupplements?

Hymovis stands out for its advanced gel formulation and longer-lasting results compared to products like Synvisc or Euflexxa.

3. Can Hymovis treat joints other than the knee?

Currently, Hymovis is approved specifically for treating knee osteoarthritis and has not been studied extensively for other joints.

4. Are there any side effects?

Common side effects include temporary swelling, redness, or discomfort at the injection site. Rare side effects may include infections or allergic reactions.

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References

Pereira TV, Jüni P, Saadat P, et al. Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis. BMJ. Published online July 6, 2022:e069722. doi:https://doi.org/10.1136/bmj-2022-069722 

https://www.facebook.com/Drugscom. Hymovis Uses, Side Effects & Warnings. Drugs.com. Published 2023. https://www.drugs.com/mtm/hymovis.html